Klebsiella pneumoniae strain EuSCAPE_HR084

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR084 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is chemoheterotrophic, relying on organic compounds for energy. It typically forms chains, pairs, or singles and possesses flagella, contributing to its mobility. The optimal growth temperature for this strain is 37°C, indicating its mesophilic nature. K. pneumoniae EuSCAPE_HR084 is associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants, highlighting its broad ecological niche. It engages in a free-living biotic relationship, and its pathogenicity is notably significant in humans, where it can cause a range of serious health issues. These include bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections, among others. The strain is known for its role in neonatal sepsis and can lead to severe outcomes such as septicemia and endophthalmitis. With a single replicon and two membranes, K. pneumoniae EuSCAPE_HR084 reflects the typical characteristics of Gram-negative bacteria, which are often associated with antibiotic resistance. The strain’s ability to infect multiple hosts and cause diverse infections underlines the importance of monitoring its presence in clinical settings. Understanding its ecological versatility and pathogenic potential can aid in developing strategies to manage infections it causes, particularly in human healthcare settings where it poses a significant risk.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR084

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR084
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR084 genome assembly,

Gene Summary

Adenine Count

1156755 bp

Thymine Count

1156090 bp

Guanine Count

1567774 bp

Cytosine Count

1544305 bp

Genome Length

5424924 bp

Protein-coding Genes

4854 genes

Non-Coding Genes

312 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive5577 - 5588Not Available
IntegraseSAMEA3721116_00008Not AvailablePositive6811 - 803746700.5
uncharacterised proteinSAMEA3721116_00009Not AvailablePositive8130 - 907136075.8
Transcriptional regulatorSAMEA3721116_00010Not AvailablePositive9253 - 953711198.2
RoiSAMEA3721116_00011Not AvailablePositive9548 - 1032728437.3
Trna-asp;Not AvailableNot AvailablePositive9924 - 10000Not Available
uncharacterised proteinSAMEA3721116_00012Not AvailablePositive10311 - 1104827327.9
uncharacterised proteinSAMEA3721116_00013Not AvailablePositive11041 - 112297224.61
uncharacterised proteinSAMEA3721116_00014Not AvailablePositive11222 - 1153611508.2
uncharacterised proteinSAMEA3721116_00015Not AvailablePositive11533 - 1190113535.6

Displaying genes 1 – 10 of 5166 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00044082-oxo-dAMPC10H14N5O7PChemical structure of 2-oxo-dAMPNot available
Average347.2212Da
Monoisotopic347.0630843Da
BASm0004777(2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioateC9H8O6Chemical structure of (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate53-42-9
Average212.158Da
Monoisotopic212.033185137Da
BASm0004837(2Z)-2-hydroxypenta-2,4-dienoateC5H5O3Chemical structure of (2Z)-2-hydroxypenta-2,4-dienoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00060381-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)C34H67O10PChemical structure of 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Not available
Average666.874Da
Monoisotopic666.4471854Da
BASm0006202(2S)-2-acetamido-4-aminobutanoateC6H12N2O3Chemical structure of (2S)-2-acetamido-4-aminobutanoateNot available
Average160.173Da
Monoisotopic160.084792254Da
BASm00064565,10-dihydrophenazine 1-carboxylateC13H10N2O2Chemical structure of 5,10-dihydrophenazine 1-carboxylateNot available
Average226.235Da
Monoisotopic226.0742276Da
BASm0006855(R)-lipoateC8H14O2S2Chemical structure of (R)-lipoate1200-22-2
Average206.326Da
Monoisotopic206.0435211Da
BASm0007624lithocholoyl-CoAC45H70N7O18P3SChemical structure of lithocholoyl-CoANot available
Average1122.07Da
Monoisotopic1121.373285Da
BASm0008183(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylateC13H12N2O2Chemical structure of (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylateNot available
Average228.251Da
Monoisotopic228.0898776Da
BASm0008187(10aS)-10,10a-dihydrophenazine-1-carboxylateC13H10N2O2Chemical structure of (10aS)-10,10a-dihydrophenazine-1-carboxylateNot available
Average226.235Da
Monoisotopic226.0742276Da

Displaying 61–70 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total