Klebsiella pneumoniae strain EuSCAPE_HR084

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR084 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is chemoheterotrophic, relying on organic compounds for energy. It typically forms chains, pairs, or singles and possesses flagella, contributing to its mobility. The optimal growth temperature for this strain is 37°C, indicating its mesophilic nature. K. pneumoniae EuSCAPE_HR084 is associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants, highlighting its broad ecological niche. It engages in a free-living biotic relationship, and its pathogenicity is notably significant in humans, where it can cause a range of serious health issues. These include bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections, among others. The strain is known for its role in neonatal sepsis and can lead to severe outcomes such as septicemia and endophthalmitis. With a single replicon and two membranes, K. pneumoniae EuSCAPE_HR084 reflects the typical characteristics of Gram-negative bacteria, which are often associated with antibiotic resistance. The strain’s ability to infect multiple hosts and cause diverse infections underlines the importance of monitoring its presence in clinical settings. Understanding its ecological versatility and pathogenic potential can aid in developing strategies to manage infections it causes, particularly in human healthcare settings where it poses a significant risk.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR084

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR084
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR084 genome assembly,

Gene Summary

Adenine Count

1156755 bp

Thymine Count

1156090 bp

Guanine Count

1567774 bp

Cytosine Count

1544305 bp

Genome Length

5424924 bp

Protein-coding Genes

4854 genes

Non-Coding Genes

312 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive5577 - 5588Not Available
IntegraseSAMEA3721116_00008Not AvailablePositive6811 - 803746700.5
uncharacterised proteinSAMEA3721116_00009Not AvailablePositive8130 - 907136075.8
Transcriptional regulatorSAMEA3721116_00010Not AvailablePositive9253 - 953711198.2
RoiSAMEA3721116_00011Not AvailablePositive9548 - 1032728437.3
Trna-asp;Not AvailableNot AvailablePositive9924 - 10000Not Available
uncharacterised proteinSAMEA3721116_00012Not AvailablePositive10311 - 1104827327.9
uncharacterised proteinSAMEA3721116_00013Not AvailablePositive11041 - 112297224.61
uncharacterised proteinSAMEA3721116_00014Not AvailablePositive11222 - 1153611508.2
uncharacterised proteinSAMEA3721116_00015Not AvailablePositive11533 - 1190113535.6

Displaying genes 1 – 10 of 5166 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00021245-dehydro-4-deoxy-D-glucarateC6H6O7Chemical structure of 5-dehydro-4-deoxy-D-glucarateNot available
Average190.1076Da
Monoisotopic190.0113525Da
BASm0002146(1R,2S)-1,2-dihydronaphthalene-1,2-diolC10H10O2Chemical structure of (1R,2S)-1,2-dihydronaphthalene-1,2-diolNot available
Average162.1852Da
Monoisotopic162.0680796Da
BASm00021577-cyano-7-deazaguanineC7H5N5OChemical structure of 7-cyano-7-deazaguanineNot available
Average175.1475Da
Monoisotopic175.0494098Da
BASm00021923-(2,3-dihydroxyphenyl)propanoateC9H9O4Chemical structure of 3-(2,3-dihydroxyphenyl)propanoateNot available
Average181.1654Da
Monoisotopic181.0500838Da
BASm0002198beta-D-ribofuranoseC5H10O5Chemical structure of beta-D-ribofuranose50-69-1
Average150.1299Da
Monoisotopic150.05282343Da
BASm0002487L-galactonateC6H11O7Chemical structure of L-galactonateNot available
Average195.1473Da
Monoisotopic195.0504777Da
BASm0002593(2E)-dodecenoyl-CoAC33H52N7O17P3SChemical structure of (2E)-dodecenoyl-CoA1066-12-2
Average943.789Da
Monoisotopic943.2353235Da
BASm0002644(9Z,12Z)-octadecadienoyl-CoAC39H62N7O17P3SChemical structure of (9Z,12Z)-octadecadienoyl-CoA6709-57-5
Average1025.94Da
Monoisotopic1025.31577Da
BASm0002726(E)-3-(methoxycarbonyl)pent-2-enedioateC7H6O6Chemical structure of (E)-3-(methoxycarbonyl)pent-2-enedioateNot available
Average186.1189Da
Monoisotopic186.0164379Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da

Displaying 21–30 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total