Klebsiella pneumoniae strain EuSCAPE_HR081

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR081 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and motility, facilitated by the presence of flagella. This strain is a chemoheterotroph, deriving energy from organic compounds, and typically thrives at an optimal temperature of 37°C, classifying it as mesophilic. This bacterium exhibits diverse cellular arrangements, including chains, pairs, and singles, and is notable for its biotic relationship as a free-living organism. It is associated with a wide range of hosts, including Homo sapiens, various avian species, and multiple vertebrates, highlighting its ecological versatility. In terms of pathogenicity, Klebsiella pneumoniae strain EuSCAPE_HR081 poses significant health risks to humans, being implicated in a variety of serious infections such as bacteremia, urinary tract infections, pneumonia, and several types of abscesses. These infections can lead to severe conditions, including sepsis and neonatal sepsis, demonstrating the strain's clinical relevance and potential impact on public health. The presence of this strain in diverse host species and its ability to cause a range of diseases underline its adaptability and the importance of monitoring its spread, particularly in clinical settings where antibiotic resistance may be a concern. Understanding the ecological dynamics of Klebsiella pneumoniae can inform infection control practices and aid in the development of therapeutic strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR081

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR081
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR081 genome assembly,

Gene Summary

Adenine Count

1218042 bp

Thymine Count

1218704 bp

Guanine Count

1615255 bp

Cytosine Count

1610782 bp

Genome Length

5662783 bp

Protein-coding Genes

5142 genes

Non-Coding Genes

269 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Dna primaseSAMEA3721113_01183Not AvailableNegative1260864 - 126320685467.8
uncharacterised proteinSAMEA3721113_01184Not AvailableNegative1263203 - 12634218389.09
uncharacterised proteinSAMEA3721113_01185Not AvailableNegative1263427 - 12636458104.58
uncharacterised proteinSAMEA3721113_01186Not AvailableNegative1263642 - 12639059879.91
uncharacterised proteinSAMEA3721113_01187Not AvailableNegative1263902 - 12640816635.0
site-specific recombinase xercSAMEA3721113_01188Not AvailableNegative1264074 - 126495232890.6
uncharacterised proteinSAMEA3721113_01189Not AvailableNegative1264945 - 12651276755.08
uncharacterised proteinSAMEA3721113_01190Not AvailableNegative1265120 - 126540710531.3
predicted transcriptional regulatorSAMEA3721113_01191Not AvailableNegative1266260 - 12664728227.73
Cp4-57 prophageSAMEA3721113_01192Not AvailableNegative1266595 - 126782446148.8

Displaying genes 31 – 40 of 5411 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total