Klebsiella pneumoniae strain EuSCAPE_HR074

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR074 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, primarily functioning as a chemoheterotroph. This strain is capable of existing in various cellular arrangements, including chains, pairs, and singles, and possesses flagella, indicating motility. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. This strain is notable for its pathogenicity in humans, as it is associated with a variety of serious health effects, including bacteremia, urinary tract infections, pneumonia, and meningitis, among others. Klebsiella pneumoniae is recognized for its role in intra-abdominal infections, liver abscesses, and sepsis, posing significant health risks particularly in immunocompromised populations. Klebsiella pneumoniae strain EuSCAPE_HR074 is free-living but is also associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae, indicating its ecological versatility. The presence of this bacterium in diverse biological environments suggests a complex interaction with both host organisms and the surrounding ecosystems. The strain has one replicon and two membranes, characteristic of Gram-negative bacteria, and does not form spores. This information underscores the bacterium's adaptability and resilience in various environments, highlighting its potential for persistence in both natural and clinical settings. Understanding the ecological and biological traits of Klebsiella pneumoniae strain EuSCAPE_HR074 can inform strategies for managing its pathogenic effects in human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR074

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR074
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR074 genome assembly,

Gene Summary

Adenine Count

1162646 bp

Thymine Count

1156608 bp

Guanine Count

1563081 bp

Cytosine Count

1558811 bp

Genome Length

5441146 bp

Protein-coding Genes

4981 genes

Non-Coding Genes

214 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
carbonic anhydraseSAMEA3721106_04232Not AvailablePositive4497580 - 449824225173.3
hypoxanthine-guanine phosphoribosyltransferaseSAMEA3721106_04233Not AvailableNegative4498302 - 449883820123.3
glucose dehydrogenaseSAMEA3721106_04234Not AvailablePositive4499043 - 450143386426.9
multicopper oxidase type 3SAMEA3721106_04235Not AvailableNegative4501517 - 450311557893.0
chaperone lipoprotein yaccSAMEA3721106_04236Not AvailablePositive4503249 - 450360813376.1
uncharacterised proteinSAMEA3721106_04237Not AvailablePositive4503856 - 450426614942.9
fkbp-type peptidyl-prolyl cis-trans isomerase fkpaSAMEA3721106_04238Not AvailablePositive4504263 - 450510530007.6
protoporphyrinogen oxidaseSAMEA3721106_04239Not AvailableNegative4505318 - 450585120573.8
potassium uptake protein trkhSAMEA3721106_04240Not AvailableNegative4505863 - 450731452869.9
protein co-occurring with transport system proteinSAMEA3721106_04241Not AvailableNegative4507353 - 450796721489.8

Displaying genes 4331 – 4340 of 5195 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total