Klebsiella pneumoniae strain EuSCAPE_HR074

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR074 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, primarily functioning as a chemoheterotroph. This strain is capable of existing in various cellular arrangements, including chains, pairs, and singles, and possesses flagella, indicating motility. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. This strain is notable for its pathogenicity in humans, as it is associated with a variety of serious health effects, including bacteremia, urinary tract infections, pneumonia, and meningitis, among others. Klebsiella pneumoniae is recognized for its role in intra-abdominal infections, liver abscesses, and sepsis, posing significant health risks particularly in immunocompromised populations. Klebsiella pneumoniae strain EuSCAPE_HR074 is free-living but is also associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae, indicating its ecological versatility. The presence of this bacterium in diverse biological environments suggests a complex interaction with both host organisms and the surrounding ecosystems. The strain has one replicon and two membranes, characteristic of Gram-negative bacteria, and does not form spores. This information underscores the bacterium's adaptability and resilience in various environments, highlighting its potential for persistence in both natural and clinical settings. Understanding the ecological and biological traits of Klebsiella pneumoniae strain EuSCAPE_HR074 can inform strategies for managing its pathogenic effects in human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR074

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR074
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR074 genome assembly,

Gene Summary

Adenine Count

1162646 bp

Thymine Count

1156608 bp

Guanine Count

1563081 bp

Cytosine Count

1558811 bp

Genome Length

5441146 bp

Protein-coding Genes

4981 genes

Non-Coding Genes

214 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna topoisomerase iSAMEA3721106_03722Not AvailablePositive3971383 - 397398097301.9
cys regulon transcriptional activator cysbSAMEA3721106_03723Not AvailablePositive3974326 - 397530035965.2
uncharacterised proteinSAMEA3721106_03724Not AvailablePositive3975546 - 39757136320.91
aconitate hydrataseSAMEA3721106_03725Not AvailablePositive3976102 - 397877497556.5
gtp cyclohydrolase iiSAMEA3721106_03726Not AvailableNegative3978821 - 397942322183.7
phosphatidylglycerophosphatase bSAMEA3721106_03727Not AvailablePositive3979587 - 398035428925.2
inner membrane protein ycisSAMEA3721106_03728Not AvailablePositive3980490 - 398079811271.2
heat shock protein ycimSAMEA3721106_03729Not AvailablePositive3980805 - 398197444488.4
orotidine 5'-phosphate decarboxylaseSAMEA3721106_03730Not AvailablePositive3982166 - 398290326307.7
translation initiation factor sui1-like proteinSAMEA3721106_03731Not AvailablePositive3982903 - 398322911253.7

Displaying genes 3851 – 3860 of 5195 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total