Klebsiella pneumoniae strain EuSCAPE_HR022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR022 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. It is characterized by its ability to arrange in chains, pairs, or as single cells, and it possesses flagella, indicating mobility. This strain thrives optimally at 37°C, within a mesophilic temperature range, and has a single replicon with a double membrane structure. This bacterium is associated with a wide range of hosts, including Homo sapiens, various birds (Gallus gallus, Phasianidae), mammals (Canis lupus familiaris, Sus scrofa, Equidae), amphibians, and fish (Danio rerio). Its free-living nature allows it to adapt and persist in diverse environments, including those associated with human activity. Klebsiella pneumoniae has significant health implications, being associated with various infections such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's pathogenicity is primarily directed toward humans, contributing to a spectrum of diseases that can range from mild to severe, including neonatal sepsis and intra-abdominal infections. The ecological insight into Klebsiella pneumoniae strain EuSCAPE_HR022 highlights its role as both a commensal and a pathogen within different biological systems. Understanding its interactions within various hosts and environments can provide valuable information for managing infections and reducing the impact of this opportunistic pathogen in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR022 genome assembly,

Gene Summary

Adenine Count

1148410 bp

Thymine Count

1144353 bp

Guanine Count

1550360 bp

Cytosine Count

1535487 bp

Genome Length

5378610 bp

Protein-coding Genes

4870 genes

Non-Coding Genes

256 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
propanediol utilization polyhedral body protein pdujSAMEA3721026_00538Not AvailableNegative535131 - 5354069108.11
propanediol dehydratase reactivation factor small subunitSAMEA3721026_00539Not AvailableNegative535425 - 53577512979.6
propanediol dehydratase reactivation factor large subunitSAMEA3721026_00540Not AvailableNegative535765 - 53759763835.4
propanediol dehydratase small subunitSAMEA3721026_00541Not AvailableNegative537610 - 53813419557.2
propanediol dehydratase medium subunitSAMEA3721026_00542Not AvailableNegative538149 - 53883824485.7
propanediol dehydratase large subunitSAMEA3721026_00543Not AvailableNegative538849 - 54051360327.9
propanediol utilization polyhedral body protein pdubSAMEA3721026_00544Not AvailableNegative540532 - 54134427912.3
propanediol utilization polyhedral body protein pduaSAMEA3721026_00545Not AvailableNegative541341 - 5416259626.73
propanediol diffusion facilitatorSAMEA3721026_00546Not AvailablePositive542149 - 54295828510.5
propanediol utilization transcriptional activatorSAMEA3721026_00547Not AvailablePositive543162 - 54407334144.8

Displaying genes 711 – 720 of 5126 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total