Klebsiella pneumoniae strain EuSCAPE_HR020

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR020 is a gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is a chemoheterotroph, deriving energy from organic compounds, and is typically found in host-associated habitats. It is capable of existing in various arrangements, including chains, pairs, and singles. The optimal growth temperature for EuSCAPE_HR020 is 37°C, placing it within the mesophilic temperature range. This strain has significant pathogenic potential in humans, being associated with a variety of serious health conditions. It can cause bacteremia, urinary tract infections, pneumonia, and several other infections such as meningitis and liver abscesses. The wide range of hosts for this strain includes humans (Homo sapiens), various mammals, birds, and even plants, indicating its versatile ecological presence and potential for cross-species transmission. Klebsiella pneumoniae strain EuSCAPE_HR020 is nonsporulating and possesses a single replicon system with a double membrane structure. Its ability to thrive in diverse environments, alongside its pathogenicity, highlights its role in both clinical settings and as a component of microbial ecosystems. Understanding its ecological interactions and pathogenic mechanisms is crucial for developing effective treatment strategies against the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR020

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR020
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR020 genome assembly,

Gene Summary

Adenine Count

1199776 bp

Thymine Count

1200240 bp

Guanine Count

1625074 bp

Cytosine Count

1578141 bp

Genome Length

5603231 bp

Protein-coding Genes

4998 genes

Non-Coding Genes

343 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-fuculose phosphate aldolaseSAMEA3721022_00422Not AvailablePositive420630 - 42127723738.6
lactaldehyde reductaseSAMEA3721022_00423Not AvailablePositive421305 - 42245340232.3
dna polymerase iSAMEA3721022_00424Not AvailableNegative422524 - 42327927822.4
alkanesulfonates-binding proteinSAMEA3721022_00425Not AvailableNegative423376 - 42531971706.3
alkanesulfonate monooxygenaseSAMEA3721022_00426Not AvailablePositive425591 - 42676342537.6
fad-dependent oxidoreductaseSAMEA3721022_00427Not AvailablePositive426810 - 42820750199.2
coenzyme f420-dependent n5 n10-methylene tetrahydromethanopterin reductase-like proteinSAMEA3721022_00428Not AvailablePositive428281 - 42968752291.6
methionine abc transporter atp-binding proteinSAMEA3721022_00429Not AvailablePositive429684 - 43070636654.4
methionine abc transporter permeaseSAMEA3721022_00430Not AvailablePositive430703 - 43140124874.2
methionine abc transporter substrate-binding proteinSAMEA3721022_00431Not AvailablePositive431398 - 43227632648.3

Displaying genes 721 – 730 of 5341 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total