Klebsiella pneumoniae strain EuSCAPE_HR012

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR012 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and ability to thrive as a chemoheterotroph. This strain exhibits a diverse range of cell arrangements, including chains, pairs, and singles, and possesses flagella, indicating motility. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to the human body and various associated environments. This bacterium is primarily host-associated, with a wide array of potential hosts, including Homo sapiens, Gallus gallus, and several other metazoan species. Its pathogenicity is significant, as Klebsiella pneumoniae is known to cause various serious infections in humans, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The range of health effects also extends to infections in animals, indicating its ecological versatility. Klebsiella pneumoniae strain EuSCAPE_HR012 is nonsporulating and possesses a single replicon and two membranes, typical of Gram-negative bacteria. Its ability to establish infections in multiple hosts underscores its role in both human and veterinary medicine. The ecological implications of this strain are noteworthy, as it exemplifies the complex interactions between pathogens and their hosts, demonstrating how a single bacterial species can adapt to diverse environments and host systems, thereby contributing to its persistence and pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR012

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR012
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR012 genome assembly,

Gene Summary

Adenine Count

1159746 bp

Thymine Count

1158431 bp

Guanine Count

1566910 bp

Cytosine Count

1541698 bp

Genome Length

5426785 bp

Protein-coding Genes

4917 genes

Non-Coding Genes

163 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alpha-galactosidaseSAMEA3721004_04245Not AvailableNegative4503498 - 450485050441.6
melibiose operon regulatory proteinSAMEA3721004_04246Not AvailablePositive4505090 - 450602836192.6
proline/glycine betaine transporterSAMEA3721004_04247Not AvailableNegative4506078 - 450758054804.0
alkylphosphonate utilization operon protein phnaSAMEA3721004_04248Not AvailablePositive4508125 - 450846012249.7
protein phnbSAMEA3721004_04249Not AvailablePositive4508689 - 450912315625.6
gntr family transcriptional regulatorSAMEA3721004_04250Not AvailablePositive4509279 - 451000427820.4
phng proteinSAMEA3721004_04251Not AvailablePositive4510005 - 451045716871.3
phnh proteinSAMEA3721004_04252Not AvailablePositive4510454 - 451103820912.4
phni proteinSAMEA3721004_04253Not AvailablePositive4511039 - 451210339063.4
phnj proteinSAMEA3721004_04254Not AvailablePositive4512096 - 451294432063.3

Displaying genes 4251 – 4260 of 5080 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total