Klebsiella pneumoniae strain EuSCAPE_HR007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR007 is a facultative anaerobic, Gram-negative bacterium that exhibits a rod shape and is capable of mobility due to the presence of flagella. This strain is classified as a chemoheterotroph and thrives optimally at 37°C, falling within the mesophilic temperature range. The bacteria predominantly exist in various arrangements, including chains, pairs, and singles. As a free-living organism, K. pneumoniae strain EuSCAPE_HR007 can associate with a diverse range of hosts, including Homo sapiens, Gallus gallus, and several other Metazoa and Viridiplantae. This wide host range indicates its ecological versatility and ability to adapt to different biological environments. K. pneumoniae is known for its pathogenicity in humans, causing a variety of serious health effects such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The bacterium is also implicated in more severe conditions such as sepsis and neonatal sepsis, highlighting its clinical significance. Overall, the ecological adaptability of K. pneumoniae strain EuSCAPE_HR007, along with its potential to cause a range of infections in multiple hosts, underscores the importance of monitoring this pathogen in both clinical and environmental settings. Its ability to thrive in diverse habitats and the range of infections it can cause emphasize the need for ongoing research and surveillance to manage its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR007 genome assembly,

Gene Summary

Adenine Count

1164896 bp

Thymine Count

1158969 bp

Guanine Count

1568659 bp

Cytosine Count

1559984 bp

Genome Length

5452508 bp

Protein-coding Genes

4927 genes

Non-Coding Genes

268 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
arginine abc transporter substrate-binding proteinSAMEA3721078_04516Not AvailableNegative4760313 - 476106527645.0
arginine transport system atp-binding proteinSAMEA3721078_04517Not AvailableNegative4761065 - 476179326894.6
lipoproteinSAMEA3721078_04518Not AvailableNegative4762020 - 476253518579.8
uncharacterised proteinSAMEA3721078_04519Not AvailablePositive4762855 - 47630195792.19
membrane-associated diguanylate cyclaseSAMEA3721078_04520Not AvailablePositive4763413 - 476455243039.9
n-acetylmuramoyl-l-alanine amidaseSAMEA3721078_04521Not AvailablePositive4764584 - 476541431265.4
nucleotide di-p-sugar epimerase or dehydrataseSAMEA3721078_04522Not AvailableNegative4765411 - 476642437959.6
nad dependent epimerase/dehydratase family proteinSAMEA3721078_04523Not AvailableNegative4766512 - 476795453735.3
low-specificity l-threonine aldolaseSAMEA3721078_04524Not AvailableNegative4767965 - 476896636230.5
pyruvate dehydrogenaseSAMEA3721078_04525Not AvailableNegative4769005 - 477072362029.0

Displaying genes 4531 – 4540 of 5195 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total