Klebsiella pneumoniae strain EuSCAPE_RO124

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO124 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophic energy sources. This strain is notable for its mobility, facilitated by the presence of flagella, and typically exists in various arrangements, including chains, pairs, and singles. It thrives optimally at 37°C, classifying it as mesophilic. Ecologically, K. pneumoniae strain EuSCAPE_RO124 is host-associated, with a wide range of potential hosts, including Homo sapiens, various avian species, and other metazoans and plants. This broad host range indicates its adaptability and potential ecological impact. Clinically, this strain is significant due to its association with various serious health conditions in humans, such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The pathogenicity of K. pneumoniae is well-documented, making it a critical concern in medical microbiology. The bacterium is nonsporulating, which suggests a reliance on specific environmental conditions for survival and proliferation. Given its free-living biotic relationship, K. pneumoniae strain EuSCAPE_RO124 plays a role in both human health and disease ecology. Its ability to cause a diverse array of infections underscores the importance of monitoring and understanding its behavior in clinical and environmental contexts. Understanding such traits can aid in developing strategies to combat infections caused by this pathogen, especially in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO124

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO124
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO124 genome assembly,

Gene Summary

Adenine Count

1318760 bp

Thymine Count

1330032 bp

Guanine Count

1682342 bp

Cytosine Count

1650226 bp

Genome Length

5981360 bp

Protein-coding Genes

5079 genes

Non-Coding Genes

427 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipoproteinSAMEA3721062_04236Not AvailableNegative4466957 - 44672208547.42
pyruvate-flavodoxin oxidoreductaseSAMEA3721062_04237Not AvailablePositive4467583 - 4471110128309.0
outer membrane pore protein n, non-specificSAMEA3721062_04238Not AvailablePositive4471467 - 447259141650.7
ktsc domain proteinSAMEA3721062_04239Not AvailablePositive4472735 - 44729478202.88
universal stress protein fSAMEA3721062_04240Not AvailablePositive4473029 - 447346315958.3
trna(cytosine32)-2-thiocytidine synthetaseSAMEA3721062_04241Not AvailablePositive4473697 - 447463235387.9
atp-dependent rna helicase dbpaSAMEA3721062_04242Not AvailableNegative4474678 - 447605149186.9
zinc transporterSAMEA3721062_04243Not AvailableNegative4476577 - 447756036773.5
deor faimly transcriptional regulatorSAMEA3721062_04244Not AvailablePositive4477839 - 447858226485.8
putative oxidoreductaseSAMEA3721062_04245Not AvailablePositive4478545 - 447966340877.9

Displaying genes 4411 – 4420 of 5506 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total