Klebsiella pneumoniae strain EuSCAPE_RS103

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS103 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is known to thrive at an optimal temperature of 37°C and falls within the mesophilic temperature range. The organism is characterized by its motility and presence of flagella, which contribute to its ability to move in various environments. K. pneumoniae EuSCAPE_RS103 is typically found in host-associated habitats and displays a diverse range of biotic relationships, being free-living yet associated with multiple hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other vertebrates and invertebrates. Its pathogenic potential is significant, as it is implicated in numerous health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain possesses a single replicon and a distinctive double membrane structure. Notably, it does not undergo sporulation, which is a common feature in many other bacterial species but absent in this strain. The wide array of diseases associated with K. pneumoniae EuSCAPE_RS103 highlights its role as a serious human pathogen and underscores the importance of monitoring such strains in both clinical and ecological contexts. Understanding the ecological dynamics of K. pneumoniae can inform strategies for managing infections and preventing the spread of antibiotic-resistant strains.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS103

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS103
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS103 genome assembly,

Gene Summary

Adenine Count

1227070 bp

Thymine Count

1229645 bp

Guanine Count

1634715 bp

Cytosine Count

1606658 bp

Genome Length

5698088 bp

Protein-coding Genes

5146 genes

Non-Coding Genes

299 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
biotin--protein ligaseSAMEA3721221_05340Not AvailableNegative5594959 - 559592135433.9
udp-n-acetylenolpyruvoylglucosamine reductaseSAMEA3721221_05341Not AvailableNegative5595918 - 559694637784.2
putative resolvaseSAMEA3721221_05343Not AvailablePositive5597340 - 559793021343.8
beta-lactamase ctx-m-14SAMEA3721221_05344Not AvailableNegative5597960 - 559882630649.7
endo-beta-mannanaseSAMEA3721221_05345Not AvailablePositive5598988 - 560018745535.2
s-formylglutathione hydrolaseSAMEA3721221_05346Not AvailableNegative5601337 - 560177116130.0
s-(hydroxymethyl)glutathione dehydrogenaseSAMEA3721221_05347Not AvailableNegative5601793 - 560290239085.9
tetracycline resistance protein, efflux, class dSAMEA3721221_05348Not AvailableNegative5602997 - 560418141051.3
tetracycline repressor protein tetrSAMEA3721221_05349Not AvailablePositive5604277 - 560488522696.0
uncharacterised proteinSAMEA3721221_05350Not AvailableNegative5605707 - 560603011963.1

Displaying genes 5351 – 5360 of 5445 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total