Klebsiella pneumoniae strain EuSCAPE_RS105

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS105 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans. This strain is a facultative anaerobe and exhibits mobility due to the presence of flagella. It typically thrives at an optimal temperature of 37°C and is classified as mesophilic, indicating its preference for moderate temperature ranges. This bacterium is found in various host-associated environments, including Homo sapiens and several other species such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (domestic dogs). It displays a diverse biotic relationship by being free-living, further expanding its ecological niche. Klebsiella pneumoniae strain EuSCAPE_RS105 can cause a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Notably, it has been implicated in neonatal sepsis and various intra-abdominal infections, showcasing its clinical significance. The strain does not form spores, which may influence its survival and persistence in host environments. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_RS105 is critical for public health, particularly in managing infections associated with this pathogen. Its ability to infect multiple host species suggests potential zoonotic and environmental transmission routes, highlighting the importance of monitoring this bacterium in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS105

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS105
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS105 genome assembly,

Gene Summary

Adenine Count

1173140 bp

Thymine Count

1161220 bp

Guanine Count

1537219 bp

Cytosine Count

1587409 bp

Genome Length

5458988 bp

Protein-coding Genes

4980 genes

Non-Coding Genes

148 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcriptional regulatorSAMEA3721223_00409Not AvailablePositive430550 - 43092113146.0
Putatitive bacteriophage exodeoxyribonuclease viiiSAMEA3721223_00410Not AvailablePositive431063 - 43320179213.6
Trna-asn;Not AvailableNot AvailablePositive431619 - 431694Not Available
Trna-asn;Not AvailableNot AvailablePositive433452 - 433527Not Available
IntegraseSAMEA3721223_00411Not AvailablePositive433480 - 43460742972.5
AttrNot AvailableNot AvailablePositive434623 - 434634Not Available
5s ribosomal rnaNot AvailableNot AvailablePositive1 - 88Not Available
5s ribosomal rnaNot AvailableNot AvailablePositive11 - 125Not Available
23s ribosomal rnaNot AvailableNot AvailablePositive32 - 2931Not Available
anaerobic dimethyl sulfoxide reductase subunit cSAMEA3721223_00001Not AvailablePositive61 - 91830751.9

Displaying genes 71 – 80 of 5128 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total