Klebsiella pneumoniae strain EuSCAPE_RO123

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO123 is a Gram-negative, facultative anaerobic bacterium that exhibits a rod shape and can be found in various arrangements, including chains, pairs, and singles. This strain is a chemoheterotroph, indicating that it derives energy from organic compounds. It possesses flagella, which contribute to its mobility, and thrives optimally at 37°C within a mesophilic temperature range. EuSCAPE_RO123 has a complex biotic relationship, being free-living yet associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. This extensive host range suggests that the bacterium can adapt to diverse environments and may play varying roles in different ecosystems. Clinically, Klebsiella pneumoniae is known for its pathogenicity in humans, associated with numerous health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis. These infections can have serious implications, particularly in vulnerable populations, including neonates and immunocompromised individuals. The strain's ability to cause a variety of infections underscores its significance in medical microbiology and public health. The strain's nonsporulating nature and presence of two membranes may contribute to its resilience in host environments and potential antibiotic resistance. Understanding Klebsiella pneumoniae EuSCAPE_RO123's traits can provide insights into its ecological roles and pathogenic mechanisms, informing both clinical treatment strategies and broader ecological considerations regarding microbial interactions in host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO123

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO123
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO123 genome assembly,

Gene Summary

Adenine Count

1194237 bp

Thymine Count

1201247 bp

Guanine Count

1617136 bp

Cytosine Count

1561537 bp

Genome Length

5574157 bp

Protein-coding Genes

4972 genes

Non-Coding Genes

373 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transmembrane sugar transport proteinSAMEA3721060_01333Not AvailableNegative1360416 - 136140534422.5
sugar abc transporter atp-binding proteinSAMEA3721060_01334Not AvailableNegative1361402 - 136295256301.2
sugar abc transporter periplasmic sugar-binding proteinSAMEA3721060_01335Not AvailableNegative1362949 - 136392935180.0
biotin sulfoxide reductaseSAMEA3721060_01336Not AvailablePositive1364338 - 136664785366.7
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenaseSAMEA3721060_01337Not AvailableNegative1366755 - 136729720184.5
2,3-diketo-5-methylthio-1-phosphopentane phosphataseSAMEA3721060_01338Not AvailableNegative1367294 - 136798325519.0
methionine aminotransferaseSAMEA3721060_01339Not AvailablePositive1368110 - 136927042822.2
co-activator of prophage gene expression ibrbSAMEA3721060_01340Not AvailableNegative1369271 - 136989723573.4
co-activator of prophage gene expression ibraSAMEA3721060_01341Not AvailableNegative1369882 - 137110547902.0
lysr-family transcriptional regulator ybdoSAMEA3721060_01342Not AvailableNegative1371216 - 137214835778.2

Displaying genes 1621 – 1630 of 5345 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total