Klebsiella pneumoniae strain EuSCAPE_RO122

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO122 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. This strain is capable of mobility due to the presence of flagella and typically arranges itself in chains, pairs, or singles. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, indicating its adaptation to warm-blooded hosts. As a free-living organism, K. pneumoniae strain EuSCAPE_RO122 is associated with various hosts, including Homo sapiens, Gallus gallus, and several other animal species such as Danio rerio and Sus scrofa, as well as plants from the Viridiplantae kingdom. Its pathogenicity is notably significant in humans, where it is implicated in a range of serious health conditions. These include bacteremia, urinary tract infections, pneumonia, cystitis, and various intra-abdominal infections. Notably, it can cause neonatal sepsis and has been associated with severe complications like emphysematous pyelonephritis and endophthalmitis. The strain's ability to infect multiple hosts and cause a wide array of diseases highlights its ecological versatility and potential impact on public health. Its presence in various environments and hosts underscores the importance of monitoring and controlling Klebsiella species in clinical settings to prevent outbreaks and manage infections effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO122

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO122
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO122 genome assembly,

Gene Summary

Adenine Count

1245676 bp

Thymine Count

1255038 bp

Guanine Count

1658027 bp

Cytosine Count

1633124 bp

Genome Length

5791865 bp

Protein-coding Genes

5179 genes

Non-Coding Genes

370 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
isocitrate lyaseSAMEA3721058_05012Not AvailableNegative5270848 - 527216748415.2
malate synthaseSAMEA3721058_05013Not AvailableNegative5272232 - 527383360278.9
homoserine o-succinyltransferaseSAMEA3721058_05014Not AvailableNegative5274094 - 527502335694.3
histone acetyltransferase hpa2SAMEA3721058_05015Not AvailablePositive5275180 - 527564117379.7
uncharacterised proteinSAMEA3721058_05017Not AvailablePositive5276745 - 527767135512.4
putative transcriptional regulatorSAMEA3721058_05018Not AvailablePositive5277811 - 52779967201.78
protein of uncharacterised function (duf2857)SAMEA3721058_05019Not AvailablePositive5278185 - 527876621882.4
atp/gtp-binding protein remnantSAMEA3721058_05020Not AvailablePositive5279905 - 52801388468.02
virb1SAMEA3721058_05021Not AvailablePositive5280211 - 528092125891.6
type iv secretory pathway virb2 componentSAMEA3721058_05022Not AvailablePositive5280921 - 528121410110.7

Displaying genes 5031 – 5040 of 5549 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total