Klebsiella pneumoniae strain EuSCAPE_RO122

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO122 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. This strain is capable of mobility due to the presence of flagella and typically arranges itself in chains, pairs, or singles. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, indicating its adaptation to warm-blooded hosts. As a free-living organism, K. pneumoniae strain EuSCAPE_RO122 is associated with various hosts, including Homo sapiens, Gallus gallus, and several other animal species such as Danio rerio and Sus scrofa, as well as plants from the Viridiplantae kingdom. Its pathogenicity is notably significant in humans, where it is implicated in a range of serious health conditions. These include bacteremia, urinary tract infections, pneumonia, cystitis, and various intra-abdominal infections. Notably, it can cause neonatal sepsis and has been associated with severe complications like emphysematous pyelonephritis and endophthalmitis. The strain's ability to infect multiple hosts and cause a wide array of diseases highlights its ecological versatility and potential impact on public health. Its presence in various environments and hosts underscores the importance of monitoring and controlling Klebsiella species in clinical settings to prevent outbreaks and manage infections effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO122

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO122
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO122 genome assembly,

Gene Summary

Adenine Count

1245676 bp

Thymine Count

1255038 bp

Guanine Count

1658027 bp

Cytosine Count

1633124 bp

Genome Length

5791865 bp

Protein-coding Genes

5179 genes

Non-Coding Genes

370 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sucrose porinSAMEA3721058_00999Not AvailableNegative1010937 - 101245455653.6
fructokinaseSAMEA3721058_01000Not AvailableNegative1012619 - 101354232406.6
crp/fnr family transcriptional regulatorSAMEA3721058_01001Not AvailablePositive1013655 - 101442228442.4
gtpaseSAMEA3721058_01002Not AvailablePositive1014558 - 101490213415.4
auxiliary transport protein, mfp familySAMEA3721058_01003Not AvailablePositive1014902 - 101604441673.4
ferrichrome transport atp-binding protein fhucSAMEA3721058_01004Not AvailableNegative1016085 - 101688228858.5
iron(iii) dicitrate transport system permease protein fecdSAMEA3721058_01005Not AvailableNegative1016879 - 101796138252.2
solute-binding periplasmic protein of iron/siderophore abc transporterSAMEA3721058_01006Not AvailableNegative1017969 - 101908741325.7
uncharacterised proteinSAMEA3721058_01007Not AvailablePositive1019359 - 101974813830.0
membrane proteinSAMEA3721058_01008Not AvailablePositive1019928 - 102038316532.1

Displaying genes 1281 – 1290 of 5549 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total