Klebsiella pneumoniae strain EuSCAPE_RS085

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS085 is a Gram-negative bacterium characterized by its rod shape and the presence of flagella, which contribute to its mobility. This strain is classified as a facultative anaerobe and primarily acts as a chemoheterotroph, utilizing organic compounds as energy sources. It has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. The bacterium is typically found in host-associated environments, reflecting its free-living biotic relationship with a variety of hosts, including Homo sapiens and several animal species such as Gallus gallus, Canis lupus familiaris, and Sus scrofa, among others. This diverse host range underscores its adaptability and potential for cross-species transmission. Klebsiella pneumoniae strain EuSCAPE_RS085 is associated with various serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. These pathogenic traits highlight its role as a significant opportunistic pathogen, particularly in immunocompromised individuals. The strain's ability to cause a wide array of infections, such as pyogenic liver abscesses and neonatal sepsis, emphasizes the clinical challenges it presents in healthcare settings. With a single replicon and a double-membrane structure, Klebsiella pneumoniae demonstrates a complex cellular organization that may contribute to its virulence and resilience in diverse environments. The ecological implications of its wide host range and pathogenic potential suggest that monitoring and understanding Klebsiella pneumoniae strain EuSCAPE_RS085 is critical for public health, particularly in the context of rising antibiotic resistance and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS085

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS085
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS085 genome assembly,

Gene Summary

Adenine Count

1219106 bp

Thymine Count

1219674 bp

Guanine Count

1618326 bp

Cytosine Count

1606859 bp

Genome Length

5663965 bp

Protein-coding Genes

5157 genes

Non-Coding Genes

256 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hnh endonucleaseSAMEA3721205_00328Not AvailablePositive310499 - 31105321199.1
Hypothetical proteinSAMEA3721205_00329Not AvailablePositive311105 - 31147313458.2
Hypothetical proteinSAMEA3721205_00330Not AvailablePositive311470 - 31185313820.4
Major tail subunitSAMEA3721205_00331Not AvailablePositive311912 - 31267626919.5
Hypothetical proteinSAMEA3721205_00332Not AvailablePositive312745 - 31345827293.7
Rha proteinSAMEA3721205_00333Not AvailablePositive313675 - 31423221571.4
Hypothetical proteinSAMEA3721205_00334Not AvailableNegative314585 - 31499215330.7
MntSAMEA3721205_00335Not AvailableNegative314995 - 3152469656.46
Putative antirepressor proteinSAMEA3721205_00336Not AvailablePositive315554 - 31652836540.3
Hypothetical proteinSAMEA3721205_00337Not AvailablePositive317101 - 3173138066.95

Displaying genes 51 – 60 of 5413 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total