Klebsiella pneumoniae strain EuSCAPE_RS028

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS028 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophy as its energy source. It is capable of existing in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. This strain is mesophilic, with an optimal growth temperature of 37°C. The habitat of strain EuSCAPE_RS028 is primarily host-associated, and it has been identified in a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. This broad host range highlights the strain's adaptability and potential ecological significance. It is classified as a free-living organism, suggesting it may play roles beyond pathogenicity. Strain EuSCAPE_RS028 is associated with numerous health effects, particularly in humans, where it has been implicated in a variety of infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity is notably significant, contributing to serious health conditions, including neonatal sepsis and intra-abdominal infections. With a single replicon and a dual membrane structure, EuSCAPE_RS028 aligns with typical characteristics of other Enterobacteriaceae family members. The bacterium's ability to cause various infections underscores its importance in clinical microbiology and public health. Understanding its ecological relationships and pathogenic mechanisms can inform strategies to manage infections and explore its role in different environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS028

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS028
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS028 genome assembly,

Gene Summary

Adenine Count

1267781 bp

Thymine Count

1263568 bp

Guanine Count

1661986 bp

Cytosine Count

1660921 bp

Genome Length

5854256 bp

Protein-coding Genes

5352 genes

Non-Coding Genes

299 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein ycar in kdo2-lipid a biosynthesis clusterSAMEA3721149_01795Not AvailableNegative1897663 - 18978456797.27
uncharacterized protein conserved in bacteriaSAMEA3721149_01796Not AvailableNegative1897909 - 189913847452.0
tetraacyldisaccharide 4'-kinaseSAMEA3721149_01797Not AvailableNegative1899193 - 190017335601.3
lipid a export atp-binding/permease msbaSAMEA3721149_01798Not AvailableNegative1900170 - 190191864541.7
putative recombination protein with metallo-hydrolase domainSAMEA3721149_01799Not AvailableNegative1901955 - 190380869306.1
integration host factor subunit betaSAMEA3721149_01800Not AvailableNegative1904391 - 190467810736.8
30s ribosomal protein s1SAMEA3721149_01801Not AvailableNegative1904830 - 190650361180.5
cytidylate kinaseSAMEA3721149_01802Not AvailableNegative1906637 - 190732024875.8
3-phosphoshikimate 1-carboxyvinyltransferaseSAMEA3721149_01803Not AvailableNegative1907495 - 190877846101.4
phosphoserine aminotransferaseSAMEA3721149_01804Not AvailableNegative1908852 - 190994039671.5

Displaying genes 1991 – 2000 of 5651 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total