Klebsiella pneumoniae strain EuSCAPE_RS056

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS056 is a pathogenic, Gram-negative bacterium that primarily exhibits a rod shape and demonstrates mobility due to the presence of flagella. This strain is a facultative anaerobe, allowing it to thrive in varying oxygen conditions, and it is classified as a chemoheterotroph, utilizing organic compounds for energy. It is typically found in a host-associated habitat and can exist in various arrangements, including chains, pairs, and singles. The strain has a mesophilic temperature range, with an optimal growth temperature of 37°C, which is conducive to its survival in warm-blooded hosts. It possesses a single replicon and a double membrane structure, characteristic of its Gram-negative classification. Klebsiella pneumoniae strain EuSCAPE_RS056 has a broad range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and vertebrates. This versatility in host association underlines its ecological significance. The strain is known to cause numerous health issues in humans, including bacteremia, urinary tract infections, pneumonia, and other serious infections such as meningitis and sepsis. Its role as a pathogen in both humans and animals highlights the potential for zoonotic transmission and underscores its importance in clinical microbiology. The diversity of infections associated with K. pneumoniae strain EuSCAPE_RS056 suggests a complex interaction with its hosts, reflecting the strain's adaptability and pathogenic potential in various biological environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS056

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS056
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS056 genome assembly,

Gene Summary

Adenine Count

1191147 bp

Thymine Count

1184312 bp

Guanine Count

1585917 bp

Cytosine Count

1587613 bp

Genome Length

5548989 bp

Protein-coding Genes

5118 genes

Non-Coding Genes

196 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pyridoxal kinaseSAMEA3721177_02101Not AvailablePositive2180356 - 218121630868.5
glutathionine s-transferaseSAMEA3721177_02102Not AvailableNegative2181259 - 218186422425.1
tripeptide transporter permeaseSAMEA3721177_02103Not AvailableNegative2181975 - 218348054082.6
uncharacterised proteinSAMEA3721177_02104Not AvailablePositive2183671 - 218392810373.1
endonuclease iiiSAMEA3721177_02105Not AvailableNegative2184088 - 218472323405.5
electron transport complex protein rnfeSAMEA3721177_02106Not AvailableNegative2184725 - 218542324554.8
electron transport complex protein rnfgSAMEA3721177_02107Not AvailableNegative2185426 - 218604922141.5
electron transport complex protein rnfdSAMEA3721177_02108Not AvailableNegative2186057 - 218710937784.8
electron transport complex protein rnfcSAMEA3721177_02109Not AvailableNegative2187110 - 218937180468.4
electron transport complex protein rnfbSAMEA3721177_02110Not AvailableNegative2189364 - 218994220453.0

Displaying genes 2211 – 2220 of 5314 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total