Klebsiella pneumoniae strain EuSCAPE_RS057

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS057 is a Gram-negative bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain typically exhibits a rod shape and can be found in various cell arrangements, including chains, pairs, and singles. It possesses flagella, indicating its mobility, and operates optimally at a temperature of 37°C, within a mesophilic temperature range. The strain is associated with a wide array of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various species within the Metazoa, Viridiplantae, and other groups, highlighting its ecological versatility. Its pathogenicity is significant in humans, as it is known to cause various health complications, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. With only one replicon and two membranes, EuSCAPE_RS057 is nonsporulating, which suggests it relies on other survival strategies in its host-associated habitat. The strain's ability to thrive in diverse biological environments and its significant role in human disease underscore its importance in clinical microbiology and public health. Understanding its characteristics helps in the development of targeted interventions to manage infections caused by this organism, particularly in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS057

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS057
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS057 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

5010 genes

Non-Coding Genes

288 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
yfbuSAMEA3721178_01945Not AvailableNegative2015379 - 201587319400.2
membrane proteinSAMEA3721178_01946Not AvailableNegative2015961 - 201641617101.0
acetate kinaseSAMEA3721178_01947Not AvailablePositive2016754 - 201795643276.9
phosphate acetyltransferaseSAMEA3721178_01948Not AvailablePositive2018157 - 202030477229.7
nudix hydrolase yfcdSAMEA3721178_01949Not AvailableNegative2020397 - 202094820772.1
phosphodiesteraseSAMEA3721178_01950Not AvailableNegative2021006 - 202155720060.2
glutathione s-transferaseSAMEA3721178_01951Not AvailableNegative2021620 - 202225824000.5
glutathione s-transferaseSAMEA3721178_01952Not AvailablePositive2022439 - 202306823744.6
dihydroneopterin triphosphate epimeraseSAMEA3721178_01953Not AvailablePositive2023134 - 202349614019.8
cell division inhibitorSAMEA3721178_01954Not AvailablePositive2023515 - 202440832935.9

Displaying genes 2111 – 2120 of 5297 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total