Klebsiella pneumoniae strain EuSCAPE_RS032

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS032 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, categorizing it as a chemoheterotroph. This strain is capable of existing in various cellular arrangements, including chains, pairs, and singles, and possesses flagella, indicating motility. It thrives optimally at 37°C, making it well-suited to the human body, as well as other hosts such as Gallus gallus (chickens) and various mammals. This strain is associated with a wide array of health concerns in humans, notably including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The extensive list of health effects underscores its pathogenic potential and highlights its role as a significant opportunistic pathogen. It is nonsporulating and has a biotic relationship characterized as free-living, indicating its adaptability to different environments, including those associated with its diverse hosts. Klebsiella pneumoniae strain EuSCAPE_RS032 is notable not only for its pathogenicity in humans but also for its presence in various other species, including livestock and companion animals. This broad host range suggests that the strain can thrive in multiple ecological niches, potentially contributing to its resilience and ability to spread between different hosts. Understanding the interactions between this pathogen and its hosts can provide insight into infection control and prevention strategies, especially in healthcare settings where it poses a significant risk to vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS032

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS032
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS032 genome assembly,

Gene Summary

Adenine Count

1210534 bp

Thymine Count

1207426 bp

Guanine Count

1617899 bp

Cytosine Count

1610011 bp

Genome Length

5645870 bp

Protein-coding Genes

5128 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3721153_00818Not AvailableNegative811841 - 81221813992.2
AttrNot AvailableNot AvailablePositive812313 - 812359Not Available
Tmrna,resume;Not AvailableNot AvailablePositive812315 - 812677Not Available
Ssra-binding proteinSAMEA3721153_00820Not AvailableNegative812822 - 81330418240.1
Type ii toxin-antitoxin system toxin rataSAMEA3721153_00821Not AvailablePositive813454 - 81389116039.5
Rnfh family proteinSAMEA3721153_00822Not AvailablePositive813881 - 81417110821.0
Outer membrane protein assembly factor bameSAMEA3721153_00823Not AvailableNegative814238 - 81457912414.0
Dna repair protein recnSAMEA3721153_00824Not AvailableNegative814727 - 81638861373.2
Dna repair protein recnSAMEA3721153_00825Not AvailableNegative816475 - 81735332410.0
Heat shock proteinSAMEA3721153_00826Not AvailablePositive817478 - 81806821751.9

Displaying genes 81 – 90 of 5434 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total