Klebsiella pneumoniae strain EuSCAPE_HR090

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR090 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. It exhibits a diverse cell arrangement, occurring in chains, pairs, and singles, and possesses flagella, enabling mobility. This strain thrives optimally at 37°C within a mesophilic temperature range and has a single replicon and double membrane structure. K. pneumoniae is primarily host-associated and exhibits free-living behaviors in various environments. It can infect multiple hosts, including Homo sapiens, various avian species like Gallus gallus and Phasianidae, as well as other vertebrates such as Danio rerio, Sus scrofa, and Canis lupus familiaris. The pathogenic potential of K. pneumoniae strain EuSCAPE_HR090 is significant, as it is associated with a wide range of health effects in humans. These include serious conditions such as bacteremia, urinary tract infections, pneumonia, cystitis, and various intra-abdominal infections. In addition, it can lead to severe complications like liver abscesses, meningitis, and sepsis, highlighting its clinical relevance. The ecological and biological insights related to this strain underscore its adaptability and potential for zoonotic transmission, linking its presence in both human and animal hosts. This adaptability may facilitate its persistence in diverse environments, raising public health concerns regarding infection control and antibiotic resistance. Understanding its ecology and pathogenicity is crucial for developing effective strategies to mitigate its impact on human health and manage its spread across different hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR090

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR090
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR090 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4458 genes

Non-Coding Genes

608 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenaseSAMEA3721133_02282Not AvailableNegative2381597 - 238213920269.6
2,3-diketo-5-methylthio-1-phosphopentane phosphataseSAMEA3721133_02283Not AvailableNegative2382136 - 238282525519.0
methionine aminotransferaseSAMEA3721133_02284Not AvailablePositive2382952 - 238411242786.2
co-activator of prophage gene expression ibrbSAMEA3721133_02285Not AvailableNegative2384113 - 238473923573.4
co-activator of prophage gene expression ibraSAMEA3721133_02286Not AvailableNegative2384724 - 238594747902.0
lysr-family transcriptional regulator ybdoSAMEA3721133_02287Not AvailableNegative2386058 - 238699035778.2
thiol:disulfide interchange protein dsbgSAMEA3721133_02288Not AvailableNegative2387171 - 238792027923.2
alkyl hydroperoxide reductase protein cSAMEA3721133_02289Not AvailablePositive2388332 - 238889520764.5
alkyl hydroperoxide reductase protein fSAMEA3721133_02290Not AvailablePositive2389083 - 239064856021.9
universal stress protein gSAMEA3721133_02291Not AvailableNegative2390725 - 239115315953.4

Displaying genes 2461 – 2470 of 5066 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total