Klebsiella pneumoniae strain EuSCAPE_HR089

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR089 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of mobility, possessing flagella, and typically exists in various cellular arrangements, including chains, pairs, and singles. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. This strain is predominantly host-associated and demonstrates a free-living biotic relationship with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and vertebrates. Notably, K. pneumoniae is recognized for its significant pathogenicity in humans, being implicated in numerous health concerns such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. K. pneumoniae strain EuSCAPE_HR089 is nonsporulating and features a single replicon and a double membrane structure. Its association with multiple hosts suggests an ecological versatility that enables its survival in various environments, both human and animal. The extensive range of health effects associated with this strain underscores its importance in clinical microbiology and public health, highlighting the need for ongoing surveillance and research to address its impact on both human health and the broader ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR089

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR089
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR089 genome assembly,

Gene Summary

Adenine Count

1175883 bp

Thymine Count

1165267 bp

Guanine Count

1544525 bp

Cytosine Count

1580006 bp

Genome Length

5465681 bp

Protein-coding Genes

4932 genes

Non-Coding Genes

264 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive1152196 - 1152207Not Available
Tail spikeSAMEA3721121_01084Not AvailableNegative1157852 - 115993974205.8
Putative tail proteinSAMEA3721121_01085Not AvailableNegative1159982 - 116245691905.4
Tail assembly proteinSAMEA3721121_01086Not AvailableNegative1162443 - 116283814782.9
Hypothetical proteinSAMEA3721121_01087Not AvailableNegative1162835 - 116330517462.6
Hypothetical proteinSAMEA3721121_01088Not AvailableNegative1163305 - 116378118164.4
uncharacterised proteinSAMEA3721121_01089Not AvailableNegative1163824 - 11640698914.61
Tail length tape measure proteinSAMEA3721121_01090Not AvailableNegative1164069 - 116570357346.2
Hypothetical proteinSAMEA3721121_01091Not AvailableNegative1167228 - 116756912955.7
uncharacterised proteinSAMEA3721121_01092Not AvailablePositive1167785 - 116836321332.2

Displaying genes 1 – 10 of 5196 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
EpnCausesPMC7480896
Emphysematous pyelonephritisCausesPMC7480896
Pulmonary infectionCausesPMC8190614
Primary bacteremiaCausesPMC9427560
Urinary tract infectionsCausesPMC9427560
PneumoniaCausesPMC9427560
Intra-abdominal infectionsCausesPMC9427560
Wound infectionsCausesPMC9427560
PyonephrosisCausesPMC11729731
Psoas abscessCausesPMC11729731

Displaying health effects 31 – 40 of 53 in total