Klebsiella pneumoniae strain EuSCAPE_UK029

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK029 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, primarily functioning as a chemoheterotroph. This strain is known to form chains, pairs, and singles, and possesses flagella, enabling mobility. The optimal growth temperature for this mesophilic organism is 37°C. This strain is associated with a variety of hosts, including Homo sapiens and other species such as Gallus gallus (chickens), Danio rerio (zebrafish), and Canis lupus familiaris (domestic dogs). Its free-living nature allows it to thrive in diverse environments, making it versatile in terms of ecological interactions. Klebsiella pneumoniae strain EuSCAPE_UK029 is clinically significant due to its association with numerous health issues in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. This strain's pathogenicity is particularly noted in its role in bloodstream infections and sepsis, which can be severe and life-threatening. The range of health effects underscores its potential impact on both human and animal hosts. The presence of this bacterium in various hosts indicates its ecological adaptability and suggests a complex interplay between the organism and its environment, including the potential for zoonotic transmission. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_UK029 is crucial for addressing its role in human health and developing strategies for infection control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK029

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK029
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK029 genome assembly,

Gene Summary

Adenine Count

1212035 bp

Thymine Count

1207996 bp

Guanine Count

1606061 bp

Cytosine Count

1609867 bp

Genome Length

5635959 bp

Protein-coding Genes

5033 genes

Non-Coding Genes

459 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
endoribonuclease symeSAMEA3720917_00842Not AvailableNegative873676 - 87398410887.9
6-phospho-beta-glucosidase ascbSAMEA3720917_00843Not AvailableNegative874166 - 87559053734.7
pts system proteinSAMEA3720917_00844Not AvailableNegative875617 - 87705950317.9
ascbf operon repressorSAMEA3720917_00845Not AvailablePositive877327 - 87834036998.7
electron transport protein hydnSAMEA3720917_00846Not AvailablePositive878477 - 87900419154.3
hydrogenase metallocenter assembly protein hypfSAMEA3720917_00847Not AvailablePositive879013 - 88124779559.9
hoxn/hupn/nixa family nickel/cobalt transporterSAMEA3720917_00848Not AvailablePositive881244 - 88225736262.5
fad-dependent pyridine nucleotide-disulfide oxidoreductaseSAMEA3720917_00849Not AvailableNegative882354 - 88348740908.6
anaerobic nitric oxide reductase flavorubredoxinSAMEA3720917_00850Not AvailableNegative883484 - 88493254421.4
anaerobic nitric oxide reductase transcription regulator norrSAMEA3720917_00851Not AvailablePositive885120 - 88667055954.2

Displaying genes 1261 – 1270 of 5492 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total