Klebsiella pneumoniae strain EuSCAPE_UK026

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK026 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism, making it capable of thriving in both aerobic and anaerobic environments. This strain exhibits mobility due to the presence of flagella and is typically found in various arrangements, including chains, pairs, and singles. It is classified as a chemoheterotroph, utilizing organic compounds as energy sources. The optimal growth temperature for EuSCAPE_UK026 is 37°C, placing it within the mesophilic temperature range. This strain contains a single replicon and possesses a double membrane structure, characteristic of Gram-negative bacteria. Its biotic relationships indicate that it is free-living but is also associated with numerous hosts, including Homo sapiens, Gallus gallus, and various species across Metazoa and Viridiplantae, indicating its ecological versatility. Clinically, K. pneumoniae strain EuSCAPE_UK026 is significant due to its pathogenicity in humans, being implicated in a wide array of health issues. These include bacteremia, urinary tract infections, pneumonia, and various forms of sepsis, among others. The strain's ability to cause severe infections underscores its role as an opportunistic pathogen, particularly in immunocompromised individuals. The presence of K. pneumoniae in diverse hosts suggests an ecological adaptability that may facilitate its transmission and persistence in various environments, posing a continuous public health challenge. Understanding the traits and pathogenic potential of this strain is essential for developing effective treatment strategies and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK026

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK026
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK026


Gene Summary

Adenine Count

0 bp

Thymine Count

0 bp

Guanine Count

0 bp

Cytosine Count

0 bp

Genome Length

0 bp

Protein-coding Genes

5060 genes

Non-Coding Genes

275 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thiol:disulfide interchange protein dsbgSAMEA3720914_00279Not AvailablePositive295818 - 29656727923.2
lysr-family transcriptional regulator ybdoSAMEA3720914_00280Not AvailablePositive296748 - 29768035778.2
co-activator of prophage gene expression ibraSAMEA3720914_00281Not AvailablePositive297791 - 29901447902.0
co-activator of prophage gene expression ibrbSAMEA3720914_00282Not AvailablePositive298999 - 29962523573.4
methionine aminotransferaseSAMEA3720914_00283Not AvailableNegative299626 - 30078642830.2
2,3-diketo-5-methylthio-1-phosphopentane phosphataseSAMEA3720914_00284Not AvailablePositive300913 - 30160225489.0
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenaseSAMEA3720914_00285Not AvailablePositive301599 - 30214120269.6
biotin sulfoxide reductaseSAMEA3720914_00286Not AvailableNegative302249 - 30455885328.5
sugar abc transporter periplasmic sugar-binding proteinSAMEA3720914_00287Not AvailablePositive304966 - 30594635180.0
sugar abc transporter atp-binding proteinSAMEA3720914_00288Not AvailablePositive305943 - 30749356329.2

Displaying genes 511 – 520 of 5335 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total