Klebsiella pneumoniae strain EuSCAPE_RO004

Klebsiella pneumoniae strain EuSCAPE_RO004 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. It typically resides in host-associated environments, indicating its dependence on biological hosts for survival. This strain is capable of existing in various forms, including chains, pairs, and singles, and it possesses flagella, which contribute to its mobility. Optimal growth temperature for EuSCAPE_RO004 is 37°C, placing it within the mesophilic temperature range. It has a simple genomic structure with one replicon and features a double membrane system typical of Gram-negative bacteria. The strain exhibits a free-living biotic relationship, albeit primarily associated with a wide array of hosts, including Homo sapiens and various other species such as Gallus gallus, Danio rerio, and Canis lupus familiaris. Notably, Klebsiella pneumoniae strain EuSCAPE_RO004 is linked to numerous health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity in humans is particularly concerning due to its association with severe clinical conditions such as neonatal sepsis and emphysematous pyelonephritis. The ecological insight drawn from the wide host range of this strain highlights its adaptability to diverse environments and hosts, which may facilitate its transmission and persistence. This adaptability underscores the importance of monitoring Klebsiella pneumoniae in clinical settings, given its potential to cause serious infections across a variety of species, including humans.