Klebsiella pneumoniae strain EuSCAPE_RO039

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO039 is a Gram-negative, rod-shaped bacterium known for its pathogenic potential in humans. It is classified as a facultative anaerobe, which means it can thrive in both oxygen-rich and oxygen-poor environments. This strain typically forms chains, pairs, and singles, and possesses flagella, which contribute to its mobility. As a chemoheterotroph, EuSCAPE_RO039 derives energy from organic compounds, making it dependent on host organisms. It is associated with a wide range of hosts, including Homo sapiens, various birds (Gallus gallus, Phasianidae, Aves), mammals (Canis lupus familiaris, Sus scrofa, Equidae), and aquatic life (Danio rerio, Amphibia). Its ecological versatility underscores the potential for cross-species transmission and adaptability in diverse environments. The strain is mesophilic, with an optimal growth temperature of 37°C, aligning with the body temperature of warm-blooded hosts. This characteristic, along with its two-membrane structure and singular replicon, indicates a well-adapted organism for life within host-associated habitats. Klebsiella pneumoniae strain EuSCAPE_RO039 is implicated in a variety of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The high pathogenicity towards humans highlights the strain's significant public health concerns, especially in hospital settings where it may lead to severe infections. In summary, the ecological and biological traits of Klebsiella pneumoniae strain EuSCAPE_RO039 underscore its adaptability and pathogenicity, revealing the extensive impact it can have on human health and the importance of monitoring its spread across different host species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO039

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO039
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO039 genome assembly,

Gene Summary

Adenine Count

1212186 bp

Thymine Count

1217815 bp

Guanine Count

1626252 bp

Cytosine Count

1598491 bp

Genome Length

5654744 bp

Protein-coding Genes

5079 genes

Non-Coding Genes

266 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Repressor protein c2SAMEA3673140_03534Not AvailableNegative3731591 - 373221722842.6
Prophage anti-repressorSAMEA3673140_03535Not AvailablePositive3732317 - 37325328108.34
Hypothetical proteinSAMEA3673140_03536Not AvailablePositive3732555 - 373311220584.4
Uncharacterized phage-encoded proteinSAMEA3673140_03537Not AvailablePositive3733287 - 373408129353.3
uncharacterised proteinSAMEA3673140_03538Not AvailablePositive3734084 - 37342637195.76
O protein family proteinSAMEA3673140_03539Not AvailablePositive3734260 - 373530938271.7
Putative dna methyltransferaseSAMEA3673140_03540Not AvailablePositive3735306 - 373619632905.8
Putative methylaseSAMEA3673140_03541Not AvailablePositive3736189 - 373791662708.0
Hypothetical proteinSAMEA3673140_03542Not AvailablePositive3737913 - 373897439737.8
Putative antitermination protein qSAMEA3673140_03543Not AvailablePositive3738996 - 373969426865.0

Displaying genes 111 – 120 of 5345 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total