Klebsiella pneumoniae strain EuSCAPE_RO026

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO026 is a gram-negative, rod-shaped bacterium known for its pathogenicity in humans and various animal hosts, including Homo sapiens, Gallus gallus, and Sus scrofa, among others. This strain is classified as a facultative anaerobe and exhibits mobility, facilitated by the presence of flagella. Its optimal growth temperature is 37°C, indicating it thrives in warm-blooded hosts, while it is also categorized as mesophilic, able to grow within a specific temperature range. As a chemoheterotroph, Klebsiella pneumoniae strain EuSCAPE_RO026 utilizes organic compounds as its energy source. The bacterium typically arranges itself in chains, pairs, or as single cells. It possesses a unique biotic relationship, being free-living and associated with a variety of hosts, which may contribute to its transmission and adaptability in different environments. The strain is known to cause a range of health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its pathogenic potential is underscored by its ability to lead to severe conditions such as sepsis, neonatal sepsis, and pulmonary infections. Given its wide host range and significant disease associations, Klebsiella pneumoniae strain EuSCAPE_RO026 highlights the importance of monitoring such pathogens in both clinical and environmental contexts. This emphasizes the need for ongoing surveillance and research to mitigate the risks associated with its transmission and pathogenicity across diverse species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO026

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO026
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO026 genome assembly,

Gene Summary

Adenine Count

1221569 bp

Thymine Count

1220212 bp

Guanine Count

1634062 bp

Cytosine Count

1607122 bp

Genome Length

5682965 bp

Protein-coding Genes

5088 genes

Non-Coding Genes

389 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
deoxyribonucleaseSAMEA3673127_03459Not AvailableNegative3612384 - 361317829532.1
dna polymerase iii subunit delta'SAMEA3673127_03460Not AvailableNegative3613189 - 361419337168.1
thymidylate kinaseSAMEA3673127_03461Not AvailableNegative3614190 - 361483123557.2
protein yceg like proteinSAMEA3673127_03462Not AvailableNegative3614821 - 361584338409.7
aminodeoxychorismate lyaseSAMEA3673127_03463Not AvailableNegative3615845 - 361665430260.3
3-oxoacyl-(acyl carrier protein) synthase iiSAMEA3673127_03464Not AvailableNegative3616780 - 361802142862.0
acyl carrier proteinSAMEA3673127_03465Not AvailableNegative3618111 - 36183478639.99
3-oxoacyl-acp reductaseSAMEA3673127_03466Not AvailableNegative3618558 - 361929225511.8
malonyl coa-acyl carrier protein transacylaseSAMEA3673127_03467Not AvailableNegative3619305 - 362023432342.9
3-oxoacyl-acp synthaseSAMEA3673127_03468Not AvailableNegative3620250 - 362120333423.9

Displaying genes 3601 – 3610 of 5477 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total