Klebsiella pneumoniae strain EuSCAPE_RO016

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO016 is a facultative anaerobic, gram-negative bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain is classified as a chemoheterotroph, deriving energy from organic compounds, and is typically found in host-associated environments. It can exist in various arrangements, including chains, pairs, and singles, and thrives optimally at 37°C, indicating its adaptation to warm-blooded hosts. K. pneumoniae strain EuSCAPE_RO016 is associated with a wide range of hosts, including Homo sapiens, various avian species, and other metazoans, highlighting its ecological versatility. This adaptability may contribute to its pathogenic potential, as it is recognized for causing numerous health issues in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain does not form spores, which is consistent with other members of the Klebsiella genus. The pathogenicity of K. pneumoniae strain EuSCAPE_RO016 is particularly significant in clinical settings, where it is implicated in severe infections such as liver abscesses and meningitis. Its ability to inhabit diverse hosts suggests a complex ecological role, potentially influencing both host health and the dynamics of infectious diseases. Understanding this strain's characteristics can aid in developing targeted treatments and management strategies for infections, emphasizing the importance of ongoing research in microbial pathogenicity and ecology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO016

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO016
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO016


Gene Summary

Adenine Count

1237417 bp

Thymine Count

1243570 bp

Guanine Count

1654975 bp

Cytosine Count

1629578 bp

Genome Length

5765540 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative inner membrane proteinSAMEA3673117_00366Not AvailableNegative389975 - 3902239515.16
uncharacterised proteinSAMEA3673117_00367Not AvailableNegative390413 - 3905233997.1
cation-transporting p-type atpaseSAMEA3673117_00368Not AvailablePositive390726 - 39344998534.1
rnd efflux membrane fusion proteinSAMEA3673117_00369Not AvailablePositive393502 - 39458138826.5
rnd multidrug efflux transporter, acriflavin resistance proteinSAMEA3673117_00370Not AvailablePositive394595 - 397687111439.0
lipoproteinSAMEA3673117_00371Not AvailableNegative398035 - 39876926997.2
carboxylate-amine ligaseSAMEA3673117_00372Not AvailableNegative398817 - 39993241789.6
drug/metabolite transporter permeaseSAMEA3673117_00373Not AvailableNegative400054 - 40097732321.7
gntr family transcriptional regulator domain / aspartate aminotransferaseSAMEA3673117_00374Not AvailablePositive401087 - 40242148974.9
gntr family transcriptional regulatorSAMEA3673117_00375Not AvailableNegative402418 - 40388154928.4

Displaying genes 631 – 640 of 5458 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total