Klebsiella pneumoniae strain EuSCAPE_RO021

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO021 is a Gram-negative, facultative anaerobic rod-shaped bacterium that is classified as a chemoheterotroph. This strain typically forms chains, pairs, or singles and possesses flagella, indicating motility. It thrives optimally at 37°C, which is within the mesophilic temperature range. The bacterium is free-living and has a single replicon with a double membrane structure. Klebsiella pneumoniae is known for its significant pathogenicity in humans, associated with a range of health conditions including bacteremia, urinary tract infections, pneumonia, cystitis, and various intra-abdominal infections. It can also lead to severe complications such as liver abscesses, meningitis, and sepsis, making it a critical concern in clinical microbiology. This strain has been identified in multiple hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and vertebrates, indicating a versatile ecological niche and potential for cross-species transmission. Its ability to inhabit diverse biological environments underlines the importance of monitoring this bacterium in both clinical and environmental settings. The broad range of infections caused by Klebsiella pneumoniae strain EuSCAPE_RO021 highlights its role as an opportunistic pathogen, particularly in individuals with compromised health. Understanding its ecological interactions and pathogenic mechanisms is essential for developing effective prevention and treatment strategies against infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO021

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO021
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO021 genome assembly,

Gene Summary

Adenine Count

1227226 bp

Thymine Count

1220432 bp

Guanine Count

1601684 bp

Cytosine Count

1619686 bp

Genome Length

5669028 bp

Protein-coding Genes

5180 genes

Non-Coding Genes

169 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pts system ascorbate-specific transporterSAMEA3673122_03143Not AvailableNegative3337948 - 333934850631.5
l-ascorbate-6-phosphate lactonase ulagSAMEA3673122_03144Not AvailablePositive3339711 - 334077540113.0
ascorbate utilization transcriptional regulator ularSAMEA3673122_03145Not AvailablePositive3340883 - 334163827365.2
esteraseSAMEA3673122_03146Not AvailableNegative3341635 - 334235126523.8
putative biofilm stress and motility protein aSAMEA3673122_03147Not AvailablePositive3342561 - 334286911321.8
membrane proteinSAMEA3673122_03148Not AvailablePositive3343007 - 33432829955.61
isovaleryl coa dehydrogenaseSAMEA3673122_03149Not AvailableNegative3343273 - 334491060624.2
23s rrna (guanosine-2'-o-)-methyltransferaseSAMEA3673122_03150Not AvailableNegative3345037 - 334576826535.3
3'-to-5' exoribonuclease rnase rSAMEA3673122_03151Not AvailableNegative3345850 - 334828291849.1
nitrite-sensitive transcriptional repressor nsrrSAMEA3673122_03152Not AvailableNegative3348319 - 334874415650.2

Displaying genes 3151 – 3160 of 5349 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total