Klebsiella pneumoniae strain EuSCAPE_RO015

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO015 is a Gram-negative, facultative anaerobic bacterium that exhibits a rod shape and is capable of mobility due to the presence of flagella. It typically forms in chains, pairs, and singles, and thrives optimally at 37°C, classifying it as mesophilic. This strain is chemoheterotrophic, deriving its energy from organic compounds. EuSCAPE_RO015 is a free-living organism primarily associated with various hosts, including Homo sapiens, Gallus gallus, and several other Metazoa and Viridiplantae. It has a notable pathogenicity towards humans, being implicated in a wide range of health complications such as bacteremia, pneumonia, urinary tract infections, and sepsis, among others. These health issues can arise from its presence in various environments, including hospital settings, where it can contribute to severe infections like pyogenic liver abscesses and endophthalmitis. The bacterium has a single replicon and is characterized by a double membrane structure, typical of Gram-negative organisms. Its ability to cause infections in both humans and other animals indicates a versatile ecological role within different biological contexts. The broad host range of Klebsiella pneumoniae strain EuSCAPE_RO015 suggests that it may play a significant role in the microbiome of various species, potentially impacting health and disease dynamics across multiple ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO015

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO015
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO015 genome assembly,

Gene Summary

Adenine Count

1218638 bp

Thymine Count

1216030 bp

Guanine Count

1616647 bp

Cytosine Count

1618212 bp

Genome Length

5669527 bp

Protein-coding Genes

5082 genes

Non-Coding Genes

390 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3673116_00068Not AvailableNegative58220 - 5856112853.7
Cell division blocking proteinSAMEA3673116_00069Not AvailableNegative58525 - 587257716.53
Regulatory proteinSAMEA3673116_00070Not AvailableNegative58733 - 5924218224.1
Rha family transcriptional regulatorSAMEA3673116_00071Not AvailableNegative59275 - 595179242.27
P2 ci-like proteinSAMEA3673116_00072Not AvailablePositive59634 - 6026623015.4
Site-specific integraseSAMEA3673116_00073Not AvailablePositive60270 - 6131039168.6
uncharacterised proteinSAMEA3673116_00074Not AvailablePositive61417 - 6234635969.9
AttrNot AvailableNot AvailablePositive62432 - 62478Not Available
Integrase-like proteinSAMEA3673116_00075Not AvailablePositive62643 - 6389048160.4
AttrNot AvailableNot AvailablePositive76213 - 76224Not Available

Displaying genes 61 – 70 of 5472 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total