Klebsiella pneumoniae strain EuSCAPE_RO091

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO091 is a notable Gram-negative bacterium classified as a chemoheterotroph, utilizing organic compounds as its energy source. This strain is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. Its rod-shaped morphology is characterized by arrangements in chains, pairs, and singles, and it exhibits mobility due to the presence of flagella. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. K. pneumoniae EuSCAPE_RO091 is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants. This bacterium has been linked to numerous health conditions in humans, such as bacteremia, urinary tract infections, pneumonia, and sepsis, indicating its significant pathogenic potential. Infections caused by this strain can lead to serious complications, including liver abscesses and wound infections, highlighting its role in both community-acquired and healthcare-associated infections. The strain has a single replicon and possesses a double membrane structure typical of Gram-negative bacteria. It does not form spores, which is consistent with its free-living biotic relationship. The extensive range of hosts and the array of health effects associated with K. pneumoniae EuSCAPE_RO091 underscore its ecological versatility. This adaptability may contribute to its persistence in various environments and its ability to cause infections across multiple species, including humans and other animals. Understanding the traits of this strain is essential for developing strategies to mitigate its pathogenic effects in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO091

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO091
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO091 genome assembly,

Gene Summary

Adenine Count

1147832 bp

Thymine Count

1153117 bp

Guanine Count

1564571 bp

Cytosine Count

1531269 bp

Genome Length

5396789 bp

Protein-coding Genes

4901 genes

Non-Coding Genes

176 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3721000_02608Not AvailablePositive2763875 - 276439919208.0
Hypothetical proteinSAMEA3721000_02609Not AvailablePositive2764396 - 276484215798.0
uncharacterised proteinSAMEA3721000_02610Not AvailablePositive2764830 - 27650337349.55
Hypothetical proteinSAMEA3721000_02611Not AvailablePositive2765020 - 276577227058.8
Hypothetical proteinSAMEA3721000_02612Not AvailablePositive2765769 - 276625117566.9
Putative tail length tape-measure proteinSAMEA3721000_02613Not AvailablePositive2766412 - 2769912125316.0
Hypothetical proteinSAMEA3721000_02614Not AvailablePositive2769909 - 277109343263.9
Putative tail assembly proteinSAMEA3721000_02615Not AvailablePositive2771080 - 277189529947.3
Tail assembly proteinSAMEA3721000_02616Not AvailablePositive2771905 - 27721509045.64
Hypothetical proteinSAMEA3721000_02617Not AvailablePositive2772161 - 27723647285.64

Displaying genes 61 – 70 of 5077 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total