Klebsiella pneumoniae strain EuSCAPE_RO084

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO084 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, enabling it to thrive in both aerobic and anaerobic environments. This strain is categorized as a chemoheterotroph, relying on organic compounds for energy. It typically forms chains, pairs, and singles, and possesses flagella, allowing for mobility. The optimal growth temperature for this strain is 37°C, which aligns with its mesophilic nature. EuSCAPE_RO084 has a unique genetic structure, characterized by a single replicon and a double membrane composition. It has been identified in various hosts, including Homo sapiens and numerous animal species such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (domestic dogs), among others. This wide host range suggests that K. pneumoniae can adapt to different biological environments, facilitating its role in diverse ecological niches. Clinically, this strain is notable for its pathogenic potential in humans, being implicated in a range of serious health issues including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The presence of K. pneumoniae in both free-living and host-associated contexts highlights its versatility and adaptability. Understanding the ecological and biological dynamics of Klebsiella pneumoniae strain EuSCAPE_RO084 can inform public health strategies, particularly in mitigating the risks associated with its pathogenicity in human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO084

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO084
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO084 genome assembly,

Gene Summary

Adenine Count

1237252 bp

Thymine Count

1240230 bp

Guanine Count

1654393 bp

Cytosine Count

1614343 bp

Genome Length

5746218 bp

Protein-coding Genes

5154 genes

Non-Coding Genes

373 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive494610 - 494621Not Available
Integrase-like proteinSAMEA3720993_00494Not AvailableNegative502396 - 50364348160.4
AttlNot AvailableNot AvailablePositive503808 - 503854Not Available
uncharacterised proteinSAMEA3720993_00495Not AvailableNegative503940 - 50486935969.9
Site-specific integraseSAMEA3720993_00496Not AvailableNegative504976 - 50601639168.6
P2 ci-like proteinSAMEA3720993_00497Not AvailableNegative506020 - 50665223015.4
Rha family transcriptional regulatorSAMEA3720993_00498Not AvailablePositive506769 - 5070119242.27
Regulatory proteinSAMEA3720993_00499Not AvailablePositive507044 - 50755318224.1
Cell division blocking proteinSAMEA3720993_00500Not AvailablePositive507561 - 5077617716.53
Hypothetical proteinSAMEA3720993_00501Not AvailablePositive507725 - 50806612853.7

Displaying genes 1 – 10 of 5527 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total