Klebsiella pneumoniae strain EuSCAPE_RO079

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO079 is a Gram-negative bacterium characterized by its rod shape and facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is known to exist in various cell arrangements, including chains, pairs, and singles, and possesses flagella, which contribute to its mobility. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. This bacterium has a diverse ecological presence, being free-living and associated with multiple hosts, including Homo sapiens, Gallus gallus, and various Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. Its pathogenicity primarily affects humans, where it can lead to a range of serious health issues, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Klebsiella pneumoniae strain EuSCAPE_RO079 is nonsporulating and consists of a single replicon and two membranes. The strain's ability to cause infections in both human and animal hosts highlights its adaptability and potential for zoonotic transmission. The extensive list of associated health effects indicates its significant impact on public health, particularly in hospital settings. Understanding the ecological and biological characteristics of this strain is essential for developing effective treatment and prevention strategies against the infections it can cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO079

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO079
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO079 genome assembly,

Gene Summary

Adenine Count

1122349 bp

Thymine Count

1130485 bp

Guanine Count

1544076 bp

Cytosine Count

1497433 bp

Genome Length

5294343 bp

Protein-coding Genes

4755 genes

Non-Coding Genes

193 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
malonate decarboxylase subunit betaSAMEA3720988_03700Not AvailablePositive3954617 - 395545029615.3
malonate decarboxylase subunit gammaSAMEA3720988_03701Not AvailablePositive3955450 - 395625028280.9
auxin efflux carrierSAMEA3720988_03702Not AvailablePositive3956387 - 395734633332.4
phosphoribosyl-dephospho-coa transferaseSAMEA3720988_03703Not AvailablePositive3957350 - 395796723015.5
malonyl coa-acyl carrier protein transacylaseSAMEA3720988_03704Not AvailablePositive3957967 - 395886932127.1
malonate utilization transcriptional regulatorSAMEA3720988_03705Not AvailableNegative3958859 - 395978534652.3
malate:quinone oxidoreductaseSAMEA3720988_03706Not AvailableNegative3959943 - 396158959971.5
glucokinase regulatory proteinSAMEA3720988_03707Not AvailableNegative3961863 - 396278332755.3
uncharacterised proteinSAMEA3720988_03708Not AvailableNegative3962947 - 396330314009.3
sensory histidine kinase dcusSAMEA3720988_03709Not AvailablePositive3963459 - 396507558944.6

Displaying genes 3801 – 3810 of 4948 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total