Klebsiella pneumoniae strain EuSCAPE_RO073

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO073 is a Gram-negative, facultative anaerobic bacterium exhibiting a rod shape and capable of mobility due to the presence of flagella. It typically exists in various arrangements, including chains, pairs, and singles. This strain is classified as a chemoheterotroph, indicating that it derives its energy from organic compounds. The optimal growth temperature for Klebsiella pneumoniae EuSCAPE_RO073 is 37°C, placing it within the mesophilic temperature range. It possesses a single replicon and is characterized by a dual membrane structure, consistent with its classification as a member of the Enterobacteriaceae family. Klebsiella pneumoniae is notably associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other animal species such as Canis lupus familiaris and Sus scrofa. This broad host range underscores its ecological versatility and significance in both wildlife and human health contexts. The strain is of particular concern in clinical settings due to its pathogenic potential. It is implicated in numerous health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The presence of Klebsiella pneumoniae in clinical cases highlights its role as a significant opportunistic pathogen, particularly in immunocompromised individuals. Given its association with multiple hosts and pathogenicity, Klebsiella pneumoniae strain EuSCAPE_RO073 exemplifies the importance of monitoring and understanding bacterial pathogens that can cross species barriers and impact both human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO073

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO073
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO073 genome assembly,

Gene Summary

Adenine Count

1182023 bp

Thymine Count

1180877 bp

Guanine Count

1571266 bp

Cytosine Count

1570977 bp

Genome Length

5505143 bp

Protein-coding Genes

4933 genes

Non-Coding Genes

233 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
drug/metabolite transporter permeaseSAMEA3720982_00110Not AvailablePositive114995 - 11589431814.9
multiple antibiotic resistance protein marbSAMEA3720982_00111Not AvailableNegative115943 - 1161618025.33
multiple antibiotic resistance protein maraSAMEA3720982_00112Not AvailableNegative116202 - 11657614698.5
dna-binding transcriptional repressor marrSAMEA3720982_00113Not AvailableNegative116597 - 11703116174.2
multiple antibiotic resistance protein marcSAMEA3720982_00114Not AvailablePositive117293 - 11796123728.9
sugar efflux transporterSAMEA3720982_00115Not AvailableNegative118030 - 11922942611.7
phenazine biosynthesis protein phzfSAMEA3720982_00116Not AvailablePositive119431 - 12022229424.0
short-chain dehydrogenase/reductase sdrSAMEA3720982_00117Not AvailableNegative120287 - 12096423352.4
yhch/yjgk/yial family proteinSAMEA3720982_00118Not AvailableNegative120961 - 12143417224.7
putative glycosyl hydrolase, bnr repeat proteinSAMEA3720982_00119Not AvailableNegative121431 - 12259742951.0

Displaying genes 281 – 290 of 5166 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total