Klebsiella pneumoniae strain EuSCAPE_RO076

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO076 is a Gram-negative, rod-shaped bacterium that exhibits a variety of pathogenic traits, primarily affecting Homo sapiens. This strain is a facultative anaerobe and a chemoheterotroph, thriving optimally at 37°C within a mesophilic temperature range. It is characterized by its ability to form chains, pairs, or exist as singles, and it exhibits mobility due to the presence of flagella. K. pneumoniae EuSCAPE_RO076 is associated with several health complications, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Other notable health effects include sepsis, neonatal sepsis, and pyogenic liver abscesses. The strain's pathogenicity is significantly relevant to human health, but it is also known to infect a range of hosts, including domesticated animals and various species of metazoans, birds, and aquatic organisms. The bacterium is nonsporulating, has a biotic relationship that allows for free living, and contains a single replicon with two membranes. Given its diverse host range and ability to cause serious infections, K. pneumoniae strain EuSCAPE_RO076 plays a significant role in both clinical and environmental microbiology. This highlights the ecological importance of understanding such pathogens, as they can adapt to various environments and hosts, potentially leading to the emergence of new pathogenic strains and complicating treatment options in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO076

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO076
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO076 genome assembly,

Gene Summary

Adenine Count

1220039 bp

Thymine Count

1216755 bp

Guanine Count

1628601 bp

Cytosine Count

1603451 bp

Genome Length

5668846 bp

Protein-coding Genes

5039 genes

Non-Coding Genes

329 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3720985_00862Not AvailableNegative947419 - 94771811218.8
Dna recombination-dependent growth factor cSAMEA3720985_00863Not AvailableNegative947808 - 94872534456.3
Regulatory proteinSAMEA3720985_00864Not AvailableNegative949439 - 95013425645.4
Hypothetical proteinSAMEA3720985_00865Not AvailablePositive950509 - 95097017291.8
Putative phage o family proteinSAMEA3720985_00866Not AvailablePositive951377 - 95229134667.7
Methyl-directed repair dna adenine methylaseSAMEA3720985_00867Not AvailablePositive952288 - 95309730326.3
Holiday-junction resolvaseSAMEA3720985_00868Not AvailablePositive953107 - 95348414296.3
Hypothetical proteinSAMEA3720985_00869Not AvailablePositive953497 - 95447736981.8
protein of uncharacterised function (duf1133)SAMEA3720985_00870Not AvailablePositive954491 - 95506921797.6
Trna,type:gly,anti_codon:tcc;Not AvailableNot AvailablePositive955239 - 955313Not Available

Displaying genes 11 – 20 of 5368 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total