Klebsiella pneumoniae strain EuSCAPE_RO056

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO056 is a gram-negative, rod-shaped bacterium characterized as a facultative anaerobe. This strain is chemoheterotrophic, utilizing organic compounds for energy, and it exhibits mobility due to the presence of flagella. It typically exists in a variety of arrangements, including chains, pairs, and singles. This organism thrives optimally at 37°C and falls within the mesophilic temperature range. It possesses a single replicon and two membranes, indicative of its cellular structure. The strain is categorized as free-living and is associated with various hosts, including Homo sapiens, Gallus gallus, and several other vertebrates and invertebrates. Klebsiella pneumoniae strain EuSCAPE_RO056 is clinically significant due to its pathogenicity in humans, where it is associated with numerous health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. It is also linked to more severe infections such as meningitis, intra-abdominal infections, and liver abscesses. The broad host range suggests a versatile ecological role, potentially facilitating its transmission between different species. The significant health impacts of this strain underscore its importance in clinical microbiology and public health, highlighting the need for ongoing surveillance and research to manage infections effectively. Overall, the strain exemplifies the complex interactions between pathogenic microorganisms and their hosts, further emphasizing the ecological implications of bacterial evolution and adaptation.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO056

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO056
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO056 genome assembly,

Gene Summary

Adenine Count

1235546 bp

Thymine Count

1247298 bp

Guanine Count

1660064 bp

Cytosine Count

1617350 bp

Genome Length

5760258 bp

Protein-coding Genes

5155 genes

Non-Coding Genes

367 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3720965_00425Not AvailablePositive434207 - 4344408678.29
Zinc-finger containing proteinSAMEA3720965_00426Not AvailablePositive434440 - 4346678309.21
Dna adenine methyltransferaseSAMEA3720965_00427Not AvailablePositive434664 - 43552132166.0
Replication endonucleaseSAMEA3720965_00428Not AvailablePositive435518 - 43793292364.4
Hypothetical proteinSAMEA3720965_00429Not AvailablePositive438086 - 4382747286.72
Dna damage inducible proteinSAMEA3720965_00430Not AvailablePositive438285 - 4385189160.16
Hypothetical proteinSAMEA3720965_00431Not AvailablePositive438633 - 43931023859.2
protein of uncharacterised function (hypoth_ymh)SAMEA3720965_00432Not AvailablePositive439589 - 44074043852.1
Portal proteinSAMEA3720965_00433Not AvailableNegative440792 - 44182639002.5
OxidoreductaseSAMEA3720965_00434Not AvailableNegative441826 - 44359266998.4

Displaying genes 11 – 20 of 5522 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total