Klebsiella pneumoniae strain EuSCAPE_RO072

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO072 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, and singles, and it possesses flagella, indicating mobility. It thrives optimally at 37°C and falls within a mesophilic temperature range. This strain is primarily associated with hosts, including Homo sapiens and various other species such as Gallus gallus, Danio rerio, and Canis lupus familiaris, among others. Its biotic relationship is categorized as free-living, allowing it to inhabit diverse environments. The pathogenic potential of K. pneumoniae strain EuSCAPE_RO072 is significant, as it is associated with a wide array of health issues in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. As a nonsporulating organism, this strain relies on its metabolic versatility and environmental adaptability to survive and thrive in host-associated habitats. The presence of a single replicon and two membranes indicates its structural characteristics typical of gram-negative bacteria. The ecological insight gained from understanding K. pneumoniae strain EuSCAPE_RO072 highlights the complex interactions this pathogen has with multiple hosts and environments. Its ability to adapt and cause a variety of infections in both humans and animals underscores the importance of monitoring its prevalence and resistance patterns, especially in clinical settings where it poses significant health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO072

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO072
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO072 genome assembly,

Gene Summary

Adenine Count

1178702 bp

Thymine Count

1176313 bp

Guanine Count

1563976 bp

Cytosine Count

1594064 bp

Genome Length

5513055 bp

Protein-coding Genes

4989 genes

Non-Coding Genes

202 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
shikimate 5-dehydrogenaseSAMEA3720981_00013Not AvailablePositive12561 - 1339729907.4
molybdenum-binding periplasmic proteinSAMEA3720981_00014Not AvailablePositive13454 - 1419726412.6
cobalamin/fe3+-siderophores abc transporter atpaseSAMEA3720981_00015Not AvailableNegative14181 - 1493026824.4
putative abc transport system permease componentSAMEA3720981_00016Not AvailableNegative14927 - 1593435192.3
putative abc transport system periplasmic binding componentSAMEA3720981_00017Not AvailableNegative15924 - 1698239343.5
dna-binding transcriptional activator mhprSAMEA3720981_00018Not AvailableNegative17074 - 1788630674.9
3-(3-hydroxyphenyl)propionate hydroxylaseSAMEA3720981_00019Not AvailablePositive18064 - 1972861627.5
2,3-dihydroxyphenylpropionate 1,2-dioxygenaseSAMEA3720981_00020Not AvailablePositive19730 - 2067434283.1
2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolaseSAMEA3720981_00021Not AvailablePositive20692 - 2155831725.2
2-keto-4-pentenoate hydrataseSAMEA3720981_00022Not AvailablePositive21569 - 2237528645.2

Displaying genes 151 – 160 of 5191 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total