Klebsiella pneumoniae strain EuSCAPE_RO067

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO067 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe and a chemoheterotroph. It is capable of mobility, possessing flagella, and typically forms chains, pairs, or exists as single cells. The strain thrives optimally at 37°C and falls within the mesophilic temperature range. This strain is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoan and plant species, suggesting a broad ecological interaction. Notably, Klebsiella pneumoniae is recognized for its pathogenicity in humans, being implicated in a range of serious health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The diverse health issues linked to this strain highlight its impact on human health and the potential for severe infections. Klebsiella pneumoniae strain EuSCAPE_RO067 does not undergo sporulation, indicating a reliance on vegetative growth for survival and reproduction. Its biotic relationships are free-living, yet it exhibits significant pathogenic capabilities, primarily affecting humans. The presence of a single replicon and two membranes aligns with the typical structure of Gram-negative bacteria, contributing to its ability to resist certain environmental stresses and antimicrobial agents. In summary, the ecological versatility and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_RO067 underscore its significance in both clinical settings and natural environments, reflecting the intricate relationships between microorganisms and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO067

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO067
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO067 genome assembly,

Gene Summary

Adenine Count

1240260 bp

Thymine Count

1240306 bp

Guanine Count

1663117 bp

Cytosine Count

1605920 bp

Genome Length

5749603 bp

Protein-coding Genes

5163 genes

Non-Coding Genes

381 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttrNot AvailableNot AvailablePositive764599 - 764610Not Available
AttlNot AvailableNot AvailablePositive2576094 - 2576139Not Available
IntegraseSAMEA3720976_02472Not AvailableNegative2576154 - 257731744300.4
Hypothetical proteinSAMEA3720976_02473Not AvailableNegative2577531 - 25777498364.9
Hypothetical proteinSAMEA3720976_02474Not AvailableNegative2577746 - 257845026898.0
Gene 24 proteinSAMEA3720976_02475Not AvailableNegative2578447 - 257871910282.4
uncharacterised proteinSAMEA3720976_02476Not AvailableNegative2578716 - 25788324301.48
Cytosine methylaseSAMEA3720976_02477Not AvailableNegative2578936 - 258007240835.2
Adenine specific methyltransferaseSAMEA3720976_02478Not AvailableNegative2580069 - 258072524234.8
Sigma-70 family rna polymerase sigma factorSAMEA3720976_02479Not AvailableNegative2580722 - 258102711155.5

Displaying genes 61 – 70 of 5544 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total