Klebsiella pneumoniae strain EuSCAPE_RO069

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO069 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of thriving in various habitats associated with hosts, including Homo sapiens and numerous other species such as Gallus gallus and Canis lupus familiaris. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. The organism typically exists in chains, pairs, or singles, and possesses flagella, allowing for mobility. It is characterized by having two membranes and a single replicon, which is indicative of its cellular structure and genetic organization. As a non-sporulating bacterium, Klebsiella pneumoniae strain EuSCAPE_RO069 demonstrates a free-living biotic relationship, although it is primarily recognized for its pathogenic potential in human hosts. Clinically, this strain is associated with a wide array of health complications, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It can lead to severe conditions such as septicemia and early onset neonatal sepsis, highlighting its significant impact on human health. The ecological insight drawn from the traits of Klebsiella pneumoniae strain EuSCAPE_RO069 suggests that its ability to adapt to diverse host species and environments may facilitate its persistence and spread in both clinical and natural settings, raising concerns about its role in public health and the potential for antibiotic resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO069

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO069
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO069 genome assembly,

Gene Summary

Adenine Count

1227879 bp

Thymine Count

1234877 bp

Guanine Count

1635919 bp

Cytosine Count

1630098 bp

Genome Length

5728773 bp

Protein-coding Genes

5121 genes

Non-Coding Genes

321 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bacterial domain of uncharacterised function (duf403)SAMEA3720978_01927Not AvailablePositive2075241 - 207617035289.3
protein containing transglutaminase-like domainSAMEA3720978_01928Not AvailablePositive2076167 - 207698230371.9
putative proteasome-type proteaseSAMEA3720978_01929Not AvailablePositive2076999 - 207774527577.8
t5orf172 domainSAMEA3720978_01930Not AvailablePositive2078225 - 207908233594.9
putative fatty acid desaturaseSAMEA3720978_01931Not AvailablePositive2079184 - 208022440178.6
phosphate/phosphonate abc transporter periplasmic proteinSAMEA3720978_01932Not AvailablePositive2080217 - 208101729091.0
dna-binding transcriptional activator tdcaSAMEA3720978_01933Not AvailablePositive2081795 - 208273634826.2
threonine dehydratase, catabolicSAMEA3720978_01934Not AvailablePositive2082830 - 208381935091.4
l-threonine transporter, anaerobically inducibleSAMEA3720978_01935Not AvailablePositive2083845 - 208517648756.5
propionate kinaseSAMEA3720978_01936Not AvailablePositive2085204 - 208641242871.5

Displaying genes 2141 – 2150 of 5442 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total