Klebsiella pneumoniae strain EuSCAPE_RO046

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO046 is a Gram-negative bacterium that exhibits a rod shape and is capable of mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It primarily relies on a chemoheterotrophic energy source. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. EuSCAPE_RO046 is associated with various hosts, including Homo sapiens and several animal species such as Gallus gallus, Canis lupus familiaris, and Sus scrofa, among others. It can exist in diverse biotic relationships, including free-living conditions. The bacterium displays a characteristic cell arrangement in chains, pairs, and singles, with a single replicon and two membranes. This strain is notably pathogenic to humans, associated with a wide array of health effects including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. These health effects underline the strain's significant role as an opportunistic pathogen, particularly in immunocompromised individuals or those with underlying health conditions. The ecological insight from the traits of Klebsiella pneumoniae strain EuSCAPE_RO046 reveals its adaptability to various environments and hosts, which may contribute to its persistence and transmission in both human and animal populations. Its potential to cause serious infections emphasizes the need for monitoring and understanding its behavior in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO046

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO046
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO046 genome assembly,

Gene Summary

Adenine Count

1195676 bp

Thymine Count

1195801 bp

Guanine Count

1608860 bp

Cytosine Count

1597553 bp

Genome Length

5597890 bp

Protein-coding Genes

5115 genes

Non-Coding Genes

281 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail fiber proteinSAMEA3720956_00001Not AvailablePositive86 - 50814932.3
Trna-glu;Not AvailableNot AvailablePositive159 - 234Not Available
Trna-ala;Not AvailableNot AvailablePositive151 - 226Not Available
Trna-thr;Not AvailableNot AvailablePositive289 - 364Not Available
Trna-ile;Not AvailableNot AvailablePositive263 - 339Not Available
Trna-thr;Not AvailableNot AvailablePositive338 - 413Not Available
Trna-gly;Not AvailableNot AvailablePositive419 - 493Not Available
Tail sheath proteinSAMEA3720956_00002Not AvailablePositive619 - 180042329.2
Trna-tyr;Not AvailableNot AvailablePositive609 - 693Not Available
Trna-thr;Not AvailableNot AvailablePositive704 - 779Not Available

Displaying genes 1 – 10 of 5396 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total