Klebsiella pneumoniae strain EuSCAPE_UK081

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK081 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is notable for its motility, aided by the presence of flagella, and it typically forms chains, pairs, or exists as single cells. Its optimal growth temperature is 37°C, classifying it as mesophilic. This bacterium is primarily host-associated, with a broad range of potential hosts including Homo sapiens, various species of birds (Gallus gallus, Phasianidae, Aves), mammals (Canis lupus familiaris, Sus scrofa, Equidae), and aquatic organisms (Danio rerio, Amphibia). The strain is involved in numerous health complications, particularly in humans, where it can lead to severe conditions such as bacteremia, pneumonia, urinary tract infections, and sepsis, among others. Klebsiella pneumoniae strain EuSCAPE_UK081 does not form spores and possesses a single replicon and a double membrane structure, typical of Gram-negative bacteria. Its free-living biotic relationship indicates that it can survive independently in various environments, although its pathogenicity in humans underscores its clinical significance. Ecologically, the ability of Klebsiella pneumoniae to associate with a wide range of hosts and its role in opportunistic infections highlight its adaptability and potential impact on public health. The strain's versatility in occupying different ecological niches may contribute to its persistent presence in both clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK081

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK081
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK081


Gene Summary

Adenine Count

1204140 bp

Thymine Count

1207981 bp

Guanine Count

1607171 bp

Cytosine Count

1606253 bp

Genome Length

5625545 bp

Protein-coding Genes

5129 genes

Non-Coding Genes

194 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
potassium voltage-gated channel subfamily kqtSAMEA3720950_00628Not AvailableNegative641442 - 64227531878.7
oligopeptide transport atp-binding protein oppfSAMEA3720950_00629Not AvailableNegative642325 - 64332937269.9
oligopeptide transport atp-binding protein oppdSAMEA3720950_00630Not AvailableNegative643326 - 64433936928.5
oligopeptide transport system permease oppcSAMEA3720950_00631Not AvailableNegative644351 - 64525933068.0
oligopeptide transport system permease oppbSAMEA3720950_00632Not AvailableNegative645274 - 64619433440.3
oligopeptide abc transporter substrate-binding protein oppaSAMEA3720950_00633Not AvailableNegative646280 - 64791461391.7
membrane proteinSAMEA3720950_00634Not AvailableNegative648652 - 64929923154.2
alcohol dehydrogenaseSAMEA3720950_00635Not AvailablePositive649776 - 65245195899.4
thymidine kinaseSAMEA3720950_00636Not AvailableNegative652599 - 65312619744.6
global dna-binding transcriptional dual regulator h-nsSAMEA3720950_00637Not AvailablePositive653778 - 65418515287.3

Displaying genes 751 – 760 of 5323 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total