Klebsiella pneumoniae strain EuSCAPE_RO043

Klebsiella pneumoniae strain EuSCAPE_RO043 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans. It is a facultative anaerobe capable of thriving in various environments, primarily associated with hosts, including Homo sapiens and several animal species such as Gallus gallus, Sus scrofa, and Canis lupus familiaris. This strain exhibits a mobility feature, characterized by the presence of flagella, and typically arranges itself in chains, pairs, or singles. As a chemoheterotroph, K. pneumoniae utilizes organic compounds as an energy source, with an optimal growth temperature of 37°C, placing it within the mesophilic temperature range. The bacterium possesses a single replicon and two membranes, indicative of its complex cell structure. K. pneumoniae strain EuSCAPE_RO043 is associated with a range of significant health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain is particularly concerning due to its potential to cause severe conditions like neonatal sepsis and septicemia, as well as infections in immunocompromised individuals. Ecologically, K. pneumoniae can exist as a free-living organism while also forming biotic relationships with a diverse array of hosts. Its ability to cause infections across multiple species highlights the strain's adaptability and pathogenic potential, emphasizing the importance of understanding its ecology and transmission pathways in both human and veterinary contexts.