Klebsiella pneumoniae strain EuSCAPE_UK067

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK067 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, and singles, and possesses flagella, indicating mobility. It has a single replicon and a double membrane structure, which is typical for bacteria within the Enterobacteriaceae family. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. EuSCAPE_UK067 is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and other metazoans and plants, demonstrating a broad ecological niche. This strain is known for its pathogenic potential in humans, capable of causing a range of serious health issues such as bacteremia, urinary tract infections, pneumonia, intra-abdominal infections, and sepsis. The wide array of diseases associated with this strain highlights its role as a significant human pathogen. Biologically, K. pneumoniae's ability to thrive in diverse environments and its pathogenic capabilities underscore its ecological versatility. The strain's associations with various hosts, including mammals and birds, suggest that it can adapt to multiple ecological niches, potentially facilitating the transmission of antimicrobial resistance genes across species. This adaptability may contribute to the increasing prevalence of infections caused by K. pneumoniae, necessitating ongoing surveillance and research to understand its epidemiology and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK067

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK067
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK067 genome assembly,

Gene Summary

Adenine Count

1236288 bp

Thymine Count

1230452 bp

Guanine Count

1632588 bp

Cytosine Count

1623408 bp

Genome Length

5722736 bp

Protein-coding Genes

5098 genes

Non-Coding Genes

417 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hydrogen peroxide-inducible genes activatorSAMEA3720941_04061Not AvailablePositive4257226 - 425814334261.9
pyridine nucleotide transhydrogenaseSAMEA3720941_04062Not AvailableNegative4258126 - 425952651535.4
unsaturated fatty acid biosynthesis repressor fabrSAMEA3720941_04063Not AvailablePositive4259723 - 426035824105.0
inner membrane proteinSAMEA3720941_04064Not AvailablePositive4260374 - 426073313030.2
trna (uracil54-c5-)-methyltransferaseSAMEA3720941_04065Not AvailableNegative4260785 - 426188541861.2
vitamin b12/cobalamin outer membrane transporterSAMEA3720941_04066Not AvailablePositive4262252 - 426409068106.4
glutamate racemaseSAMEA3720941_04067Not AvailablePositive4264035 - 426488631285.0
protoporphyrinogen oxidaseSAMEA3720941_04068Not AvailableNegative4265361 - 426589420555.8
potassium uptake protein trkhSAMEA3720941_04069Not AvailableNegative4265906 - 426735752869.9
protein co-occurring with transport system proteinSAMEA3720941_04070Not AvailableNegative4267396 - 426801021489.8

Displaying genes 4171 – 4180 of 5515 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total