Klebsiella pneumoniae strain EuSCAPE_UK065

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK065 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain typically exists in pairs, chains, or as single cells and possesses flagella, indicating mobility. It has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. This strain is notably associated with various hosts, including Homo sapiens and a range of other animals such as Gallus gallus (chickens), Canis lupus familiaris (dogs), and Sus scrofa (pigs), among others. Its pathogenicity is primarily human-focused, with a wide spectrum of associated health effects. These include severe conditions such as bacteremia, urinary tract infections, pneumonia, meningitis, and various forms of abscesses. This highlights its potential impact on both human and animal health. Klebsiella pneumoniae strain EuSCAPE_UK065 is nonsporulating and has a biotic relationship categorized as free-living. This bacterium contains a single replicon and is enveloped by two membranes, which is typical of Gram-negative organisms. The ability of this strain to thrive in diverse environments and its association with multiple hosts underscore its ecological versatility. Its role in human infections, particularly in immunocompromised individuals, highlights the relevance of monitoring and understanding its behavior in both clinical and environmental settings. Understanding the interactions of Klebsiella pneumoniae with its hosts can provide insights into its pathogenic mechanisms and potential strategies for infection control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK065

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK065
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK065 genome assembly,

Gene Summary

Adenine Count

1200258 bp

Thymine Count

1207435 bp

Guanine Count

1624805 bp

Cytosine Count

1599129 bp

Genome Length

5631627 bp

Protein-coding Genes

5051 genes

Non-Coding Genes

289 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3720940_02201Not AvailablePositive2404368 - 240471812481.8
Dna primaseSAMEA3720940_02202Not AvailablePositive2404711 - 2407473100074.0
Putative single-stranded dna-binding proteinSAMEA3720940_02203Not AvailablePositive2407591 - 240825924181.5
uncharacterised proteinSAMEA3720940_02204Not AvailablePositive2408628 - 240910117555.1
uncharacterised proteinSAMEA3720940_02205Not AvailablePositive2409285 - 24094556315.88
uncharacterised proteinSAMEA3720940_02206Not AvailablePositive2409455 - 240978112004.3
Putative tail protein (tape measure)SAMEA3720940_02207Not AvailablePositive2409789 - 2412854107549.0
AttrNot AvailableNot AvailablePositive2417949 - 2417969Not Available
AttlNot AvailableNot AvailablePositive2520325 - 2520337Not Available
Lysr family transcriptional regulatorSAMEA3720940_02319Not AvailablePositive2530171 - 253107934057.2

Displaying genes 11 – 20 of 5340 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total