Klebsiella pneumoniae strain EuSCAPE_UK049

Klebsiella pneumoniae strain EuSCAPE_UK049 is a Gram-negative, rod-shaped bacterium characterized by its arrangement in chains, pairs, and singles. This strain is a facultative anaerobe, capable of thriving in various oxygen levels, and it is classified as a chemoheterotroph, utilizing organic compounds for energy. Mobility is facilitated by the presence of flagella. K. pneumoniae EuSCAPE_UK049 has a mesophilic optimal growth temperature of 37°C and possesses a single replicon and a double membrane structure. It demonstrates a free-living biotic relationship, indicating its ability to exist independently in various environments associated with hosts. This strain is known for its significant pathogenicity in humans and is implicated in a wide range of health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It can cause severe conditions such as sepsis, meningitis, and liver abscesses. Besides human hosts, K. pneumoniae EuSCAPE_UK049 has also been associated with infections in other species, including Gallus gallus (chickens), Danio rerio (zebrafish), and various mammals, suggesting its versatility and adaptability in both human and non-human hosts. The ecological implications of K. pneumoniae EuSCAPE_UK049 underline its role in human health and disease dynamics, particularly in hospital settings where it can lead to serious infections. Its ability to colonize multiple hosts and its wide array of pathogenic effects highlight the importance of monitoring this strain in clinical microbiology and public health.