Klebsiella pneumoniae strain EuSCAPE_LU015

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_LU015 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, or occur as singles, and possesses flagella, which contributes to its mobility. It is biotically free-living but can also be associated with various hosts, including Homo sapiens, Gallus gallus, and several other animal and plant species. EuSCAPE_LU015 thrives optimally at 37°C and falls within the mesophilic temperature range. This strain has a single replicon and is surrounded by two membranes, typical of Gram-negative bacteria. Clinically, Klebsiella pneumoniae strain EuSCAPE_LU015 is notable for its pathogenicity in humans, being associated with a wide range of health effects. These include bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections, among others. The strain is implicated in severe conditions such as sepsis, neonatal sepsis, and emphysematous pyelonephritis. Understanding the diverse host range and the significant health impacts of Klebsiella pneumoniae strain EuSCAPE_LU015 highlights its ecological versatility and potential as a pathogen. Its ability to cause severe infections in multiple species underscores the importance of monitoring this bacterium in clinical settings to mitigate health risks associated with its pathogenicity.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_LU015

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_LU015
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_LU015 genome assembly,

Gene Summary

Adenine Count

1156100 bp

Thymine Count

1151616 bp

Guanine Count

1541819 bp

Cytosine Count

1552607 bp

Genome Length

5402142 bp

Protein-coding Genes

4880 genes

Non-Coding Genes

181 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
secreted proteinSAMEA3672967_01228Not AvailableNegative1334510 - 13347016805.16
Probable regulatory proteinSAMEA3672967_01229Not AvailableNegative1335094 - 13352285188.44
Putative bacteriophage regulatory proteinSAMEA3672967_01230Not AvailablePositive1335619 - 13358498519.19
Cii decision making proteinSAMEA3672967_01231Not AvailablePositive1335852 - 133638820156.3
Dna replication protein oSAMEA3672967_01232Not AvailablePositive1336798 - 133765832681.7
Replication protein pSAMEA3672967_01233Not AvailablePositive1337655 - 133839828203.0
Putative dna-binding proteinSAMEA3672967_01234Not AvailablePositive1338391 - 133872612578.4
Chromosome partitioning protein gp35SAMEA3672967_01235Not AvailablePositive1338719 - 133950428728.7
Hypothetical proteinSAMEA3672967_01236Not AvailablePositive1339501 - 13397047785.42
Hypothetical proteinSAMEA3672967_01237Not AvailablePositive1339697 - 13399519664.45

Displaying genes 11 – 20 of 5061 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total