Klebsiella pneumoniae strain EuSCAPE_LU014

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_LU014 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is a chemoheterotroph, deriving energy from organic sources, and exhibits mobility due to the presence of flagella. Typically found in chains, pairs, or as singles, EuSCAPE_LU014 has an optimal growth temperature of 37°C, categorizing it as mesophilic. EuSCAPE_LU014 is associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans, plants, and mammals, demonstrating its versatility in different biological contexts. This strain is known to have a significant impact on human health, being linked to numerous infections such as bacteremia, urinary tract infections, pneumonia, and several others, highlighting its pathogenicity. The strain has a single replicon and is nonsporulating, indicating a stable genome without the ability to enter a dormant state that some bacteria utilize for survival under adverse conditions. Its biotic relationships are characterized as free-living, yet it exhibits pathogenic behavior in humans. The ecological insight from the traits of Klebsiella pneumoniae strain EuSCAPE_LU014 suggests its adaptability and potential for causing disease across a variety of hosts. This highlights the importance of monitoring such strains in clinical settings, as their widespread presence and pathogenic potential pose significant risks to both human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_LU014

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_LU014
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_LU014 genome assembly,

Gene Summary

Adenine Count

1154878 bp

Thymine Count

1156898 bp

Guanine Count

1553124 bp

Cytosine Count

1556251 bp

Genome Length

5421151 bp

Protein-coding Genes

4971 genes

Non-Coding Genes

136 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipid a biosynthesis (kdo) 2-(lauroyl)-lipid iva acyltransferaseSAMEA3672966_00059Not AvailablePositive59629 - 6054935542.0
multidrug-efflux transporter, major facilitator superfamily (mfs)SAMEA3672966_00060Not AvailablePositive60721 - 609518262.11
multidrug-efflux transporter, major facilitator superfamily (mfs)SAMEA3672966_00061Not AvailablePositive60971 - 6194834607.5
acidic protein msybSAMEA3672966_00062Not AvailablePositive62040 - 6242614763.3
outer membrane lipoproteinSAMEA3672966_00063Not AvailableNegative62427 - 626548316.15
glucans biosynthesis glucosyltransferase hSAMEA3672966_00064Not AvailableNegative62721 - 6524996083.6
glucans biosynthesis protein gSAMEA3672966_00065Not AvailableNegative65242 - 6679558572.5
glucans biosynthesis proteinSAMEA3672966_00066Not AvailablePositive67038 - 6820744653.7
tetr family transcriptional regulatorSAMEA3672966_00067Not AvailableNegative68242 - 6883521642.8
rnase iii inhibitorSAMEA3672966_00068Not AvailableNegative68902 - 6942918401.1

Displaying genes 121 – 130 of 5107 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total