Klebsiella pneumoniae strain EuSCAPE_RS102

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS102 is a Gram-negative, rod-shaped bacterium that thrives in host-associated environments. As a facultative anaerobe, it can adapt to both aerobic and anaerobic conditions, making it versatile in various habitats. The organism is categorized as a chemoheterotroph, utilizing organic compounds for energy. Its cellular arrangement typically presents in chains, pairs, or singles, and it possesses flagella, indicating motility. EuSCAPE_RS102 is mesophilic, with an optimal growth temperature of 37°C, which corresponds to the average human body temperature, suggesting a close association with human hosts. This strain has a single replicon and dual membranes, characteristic of Gram-negative bacteria. It is involved in various biotic relationships, being free-living but predominantly pathogenic to a wide range of hosts, including Homo sapiens, Gallus gallus, and several other metazoans and vertebrates. The health implications of Klebsiella pneumoniae strain EuSCAPE_RS102 are significant, as it is associated with numerous serious conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity is particularly concerning in human health, where it can lead to severe outcomes such as neonatal sepsis and intra-abdominal infections. The presence of Klebsiella pneumoniae in diverse biological environments underscores its ecological adaptability and highlights the importance of monitoring such pathogens in both clinical and environmental settings. Understanding its various interactions within host organisms can inform public health strategies and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS102

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS102
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS102 genome assembly,

Gene Summary

Adenine Count

1178843 bp

Thymine Count

1169314 bp

Guanine Count

1569264 bp

Cytosine Count

1582862 bp

Genome Length

5500283 bp

Protein-coding Genes

4963 genes

Non-Coding Genes

315 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transporterSAMEA3721220_00416Not AvailablePositive415263 - 41665148622.6
Trna-glyNot AvailableNot AvailablePositive416819 - 416892Not Available
putative lipoproteinSAMEA3721220_00418Not AvailableNegative416973 - 41768625449.5
isopentenyl-diphosphate delta-isomeraseSAMEA3721220_00419Not AvailablePositive418003 - 41855720672.5
lysyl-trna synthetaseSAMEA3721220_00420Not AvailableNegative418792 - 42030957549.6
peptide chain release factor 2SAMEA3721220_00421Not AvailableNegative420319 - 42128135905.0
ssdna-specific exonuclease recjSAMEA3721220_00422Not AvailableNegative421503 - 42323663010.1
thiol:disulfide interchange protein dsbcSAMEA3721220_00423Not AvailableNegative423242 - 42395525427.8
tyrosine recombinase xerdSAMEA3721220_00424Not AvailableNegative423978 - 42487433969.1
flavodoxin 2SAMEA3721220_00425Not AvailablePositive424975 - 42549619543.1

Displaying genes 631 – 640 of 5278 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total