Klebsiella pneumoniae strain EuSCAPE_RS102

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS102 is a Gram-negative, rod-shaped bacterium that thrives in host-associated environments. As a facultative anaerobe, it can adapt to both aerobic and anaerobic conditions, making it versatile in various habitats. The organism is categorized as a chemoheterotroph, utilizing organic compounds for energy. Its cellular arrangement typically presents in chains, pairs, or singles, and it possesses flagella, indicating motility. EuSCAPE_RS102 is mesophilic, with an optimal growth temperature of 37°C, which corresponds to the average human body temperature, suggesting a close association with human hosts. This strain has a single replicon and dual membranes, characteristic of Gram-negative bacteria. It is involved in various biotic relationships, being free-living but predominantly pathogenic to a wide range of hosts, including Homo sapiens, Gallus gallus, and several other metazoans and vertebrates. The health implications of Klebsiella pneumoniae strain EuSCAPE_RS102 are significant, as it is associated with numerous serious conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity is particularly concerning in human health, where it can lead to severe outcomes such as neonatal sepsis and intra-abdominal infections. The presence of Klebsiella pneumoniae in diverse biological environments underscores its ecological adaptability and highlights the importance of monitoring such pathogens in both clinical and environmental settings. Understanding its various interactions within host organisms can inform public health strategies and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS102

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS102
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS102 genome assembly,

Gene Summary

Adenine Count

1178843 bp

Thymine Count

1169314 bp

Guanine Count

1569264 bp

Cytosine Count

1582862 bp

Genome Length

5500283 bp

Protein-coding Genes

4963 genes

Non-Coding Genes

315 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
osmoprotectant abc transporter permease protein yehySAMEA3721220_03760Not AvailableNegative3962145 - 396330240981.8
glycine betaine/choline abc transporter membrane proteinSAMEA3721220_03761Not AvailableNegative3963310 - 396422732858.4
beta-d-glucoside glucohydrolaseSAMEA3721220_03762Not AvailableNegative3964364 - 396666183403.6
d-lactate dehydrogenaseSAMEA3721220_03763Not AvailablePositive3966856 - 396860165324.7
n-acetyltransferase gcn5SAMEA3721220_03764Not AvailablePositive3968687 - 396924120550.7
murein-dd-endopeptidaseSAMEA3721220_03765Not AvailableNegative3969464 - 397041434686.4
inner membrane protein yohcSAMEA3721220_03766Not AvailableNegative3970603 - 397119021564.0
deda family inner membrane protein yohdSAMEA3721220_03767Not AvailablePositive3971345 - 397191421243.9
nodt family rnd efflux system outer membrane lipoproteinSAMEA3721220_03768Not AvailableNegative3971948 - 397338752231.2
6-phospho-beta-glucosidaseSAMEA3721220_03769Not AvailableNegative3973659 - 397505351799.4

Displaying genes 3931 – 3940 of 5278 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total