Klebsiella pneumoniae strain EuSCAPE_LU005

Klebsiella pneumoniae strain EuSCAPE_LU005 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophic energy sources. This strain typically exists in host-associated habitats and demonstrates mobility due to the presence of flagella. It can be found in various cell arrangements, including chains, pairs, and singles, and it possesses a mesophilic growth profile, with an optimal temperature of 37°C. The strain is nonsporulating and has a singular replicon with a double membrane structure. It has been identified in a wide range of hosts, including Homo sapiens, various birds (Gallus gallus, Phasianidae), mammals (Sus scrofa, Canis lupus familiaris, Equidae), and aquatic species (Danio rerio, Amphibia). Klebsiella pneumoniae strain EuSCAPE_LU005 is associated with numerous health effects primarily in humans, leading to conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is particularly noted for its pathogenic potential, causing severe infections that can be life-threatening, including neonatal sepsis and pyogenic liver abscesses. This strain's ability to thrive in multiple hosts and its significant role in various infectious diseases highlight its ecological versatility and public health relevance. Understanding the pathogenic mechanisms of Klebsiella pneumoniae strain EuSCAPE_LU005 is essential for developing strategies to manage and mitigate the infections it causes.